Corrosion Resistance of Ti-Si-N Coatings in Blood and Cytocompatibility with Vascular Endothelial Cells

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

Detail(s)

Original languageEnglish
Pages (from-to)45-55
Journal / PublicationVacuum
Volume128
Online published10 Mar 2016
Publication statusPublished - Jun 2016

Abstract

Ti-Si-N coatings are deposited on titanium alloy by arc-enhanced magnetron sputtering at different negative bias voltages and their corrosion resistance in blood, effects on platelet activation, endothelial cell functions are studied. The Ti-Si-N coatings are made up of crystalline TiN and amorphous Si3N4 phases and show better corrosion resistance compared with titanium alloy. Reduced platelet receptor activation is observed on the Ti-Si-N coatings and that deposited at −100 V shows the longest clotting time and smallest platelet activation. Ti-Si-N coatings also enhance the endothelial cell proliferation and spreading as well as the endothelial nitric oxide synthase (eNOS) expression.

Research Area(s)

  • Ti-Si-N coatings, Corrosion resistance, Cell proliferation, Hemocompatibility