Corrosion Resistance of Ti-Si-N Coatings in Blood and Cytocompatibility with Vascular Endothelial Cells
Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Author(s)
Detail(s)
Original language | English |
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Pages (from-to) | 45-55 |
Journal / Publication | Vacuum |
Volume | 128 |
Online published | 10 Mar 2016 |
Publication status | Published - Jun 2016 |
Link(s)
Abstract
Ti-Si-N coatings are deposited on titanium alloy by arc-enhanced magnetron sputtering at different negative bias voltages and their corrosion resistance in blood, effects on platelet activation, endothelial cell functions are studied. The Ti-Si-N coatings are made up of crystalline TiN and amorphous Si3N4 phases and show better corrosion resistance compared with titanium alloy. Reduced platelet receptor activation is observed on the Ti-Si-N coatings and that deposited at −100 V shows the longest clotting time and smallest platelet activation. Ti-Si-N coatings also enhance the endothelial cell proliferation and spreading as well as the endothelial nitric oxide synthase (eNOS) expression.
Research Area(s)
- Ti-Si-N coatings, Corrosion resistance, Cell proliferation, Hemocompatibility
Citation Format(s)
Corrosion Resistance of Ti-Si-N Coatings in Blood and Cytocompatibility with Vascular Endothelial Cells. / Zhang, Ming; Gao, Ang; Ma, Shengli; Xu, Kewei; CHU, Paul K. .
In: Vacuum, Vol. 128, 06.2016, p. 45-55.Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review