Abstract
Copper complexes of monodentate phosphoramidites efficiently promote asymmetric arylation of N-azaaryl aldimines with arylboroxines. DFT calculations and experiments support an elementary step of 1,4-insertion in the reaction pathway, a step in which an aryl-copper species adds directly across four atoms of C=N−C=N in the N-azaaryl aldimines.
| Original language | English |
|---|---|
| Pages (from-to) | 2705-2709 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 58 |
| Issue number | 9 |
| Online published | 15 Jan 2019 |
| DOIs | |
| Publication status | Published - 25 Feb 2019 |
Research Keywords
- 1,4-insertion
- arylation
- asymmetric catalysis
- copper catalysis
- phosphoramidate
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