Abstract
A hybrid neural probe (NP) structure with embedded microfluidic channel for dynamic control of NP stiffness was fabricated. The NP consisted of polydimethylsiloxane (PDMS) and polyimide (PI) layers that provided the required stiffness for insertion and also the required flexibility for the minimization of tissue damages. Moreover, the flexibility could be adjusted by varying the fluidic pressure. The minimum buckling force for a 200 μm wide and channel width of 100 μm PI NP determined to be 3.0 mN. In contrast, this value reduced to 1.1 mN for our developed PDMS/PI hybrid structure NP with the same dimensions. We found that our newly developed probe is rigid enough to penetrate the brain soft tissue and reduces the tissue damage.
| Original language | English |
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| Publication status | Published - Sept 2017 |
| Event | 43rd International Conference on Micro and Nanoengineering (MNE2017) - Braga, Portugal Duration: 18 Sept 2017 → 22 Sept 2017 http://mne2017.org/about-mne-2017-novel-items/ http://mne2017.org/wp-content/uploads/2017/10/Booklet_MNE_FINAL_WEB.pdf (Conference Booklet) |
Conference
| Conference | 43rd International Conference on Micro and Nanoengineering (MNE2017) |
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| Country/Territory | Portugal |
| City | Braga |
| Period | 18/09/17 → 22/09/17 |
| Internet address |