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Computing parametric alignment of RNA structures: Visualization and practice

Wangsen Feng, Bei Zhang, Lusheng Wang

Research output: Chapters, Conference Papers, Creative and Literary WorksRGC 32 - Refereed conference paper (with host publication)peer-review

Abstract

Alignment of RNA structures is very important in biological research. Similar to pair-wise sequence alignment, there is often disagreement about how to weight matches, mismatches, indels and gaps when comparing two RNA structures. Here, we develop a visual tool for computing parametric alignment of two RNA structures. With this tool, users can see explicitly and completely the effect of parameter choices on the optimal alignments of RNA structures. The software is available for academic use (http://www.cs.cityu.edu.hk/~lwang/ software/ParaRNA/). © 2011 IEEE.
Original languageEnglish
Title of host publicationProceedings - 2011 International Conference on Future Computer Sciences and Application, ICFCSA 2011
Pages16-18
DOIs
Publication statusPublished - 2011
Event2011 International Conference on Future Computer Sciences and Application, ICFCSA 2011 - Hong Kong, China
Duration: 18 Jun 201119 Jun 2011

Conference

Conference2011 International Conference on Future Computer Sciences and Application, ICFCSA 2011
PlaceChina
CityHong Kong
Period18/06/1119/06/11

Research Keywords

  • Parametric alignment
  • RNA structures

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