Computational Fluid Dynamics Analysis of Cold Plasma Plume Mixing with Blood Using Level Set Method Coupled with Heat Transfer

Cold plasmas were proposed for treatment of leukemia. In the present work, conceptual designs of mixing chambers that increased the contact between the two fluids (plasma and blood) through addition of obstacles within rectangular-block-shaped chambers were proposed and the dynamic mixing between the plasma and blood were studied using the level set method coupled with heat transfer. Enhancement of mixing between blood and plasma in the presence of obstacles was demonstrated. Continuous tracking of fluid mixing with determination of temperature distributions was enabled by the present model, which would be a useful tool for future development of cold plasma devices for treatment of blood-related diseases such as leukemia.