Complete Nucleotide Sequence of a Conjugative Plasmid Carrying blaPER-1

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Ruichao Li
  • Marcus Ho Yin Wong
  • Yuanjie Zhou
  • Edward Wai-chi Chan
  • Sheng Chen

Detail(s)

Original languageEnglish
Pages (from-to)3582-3584
Journal / PublicationAntimicrobial Agents and Chemotherapy
Volume59
Issue number6
Online published14 May 2015
Publication statusPublished - Jun 2015
Externally publishedYes

Abstract

The nucleotide sequence of a self-transmissible plasmid pVPH1 harboring blaPER-1 from Vibrio parahaemolyticus was determined. pVPH1 was 183,730 bp in size and shared a backbone similar to pAQU1 and pAQU2, differing mainly in an ∼40-kb multidrug resistance (MDR) region. A complex class 1 integron was identified together with ISCR1 and blaPER-1 (ISCR1-blaPER-1-gstabct-qacEΔ1-sul1), which was shown to form a circular intermediate playing an important role in the dissemination of blaPER-1.

Citation Format(s)

Complete Nucleotide Sequence of a Conjugative Plasmid Carrying blaPER-1. / Li, Ruichao; Wong, Marcus Ho Yin; Zhou, Yuanjie; Chan, Edward Wai-chi; Chen, Sheng.

In: Antimicrobial Agents and Chemotherapy, Vol. 59, No. 6, 06.2015, p. 3582-3584.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review