Comparative prevalences of Brachyspira aalborgi and Brachyspira (Serpulina) pilosicoli as etiologic agents of histologically identified intestinal spirochetosis in Australia

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

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Detail(s)

Original languageEnglish
Pages (from-to)347-350
Journal / PublicationJournal of Clinical Microbiology
Volume39
Issue number1
Publication statusPublished - Jan 2001
Externally publishedYes

Abstract

DNA from gastrointestinal biopsy specimens from 28 Australian patients with histologic evidence of intestinal spirochetosis (IS) was subjected to PCRs to amplify segments of the 16S rRNA and NADH oxidase genes of Brachyspira aalborgi and Brachyspira (Serpulina) pilosicoli. B. aalborgi was identified in specimens from 24 (85.7%) patients and B. pilosicoli in those from 4 (14.3%) patients (2 of whom were also positive forB. aalborgi). For two patients, no product was amplified. This study demonstrates that B. aalborgi is much more commonly involved in histologically identified IS in Australian patients than is B. pilosicoli. This is the first report of amplification of B. pilosicoli DNA from humans with IS.

Citation Format(s)

Comparative prevalences of Brachyspira aalborgi and Brachyspira (Serpulina) pilosicoli as etiologic agents of histologically identified intestinal spirochetosis in Australia. / MIKOSZA, ANDREW S. J.; LA, TOM; BASTIAAN DE BOER, W.; Hampson, D. J.

In: Journal of Clinical Microbiology, Vol. 39, No. 1, 01.2001, p. 347-350.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal