Combined optical and mechanical scanning in optical-resolution photoacoustic microscopy
Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review
Author(s)
Detail(s)
| Original language | English |
|---|---|
| Title of host publication | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
| Publisher | SPIE |
| Volume | 8943 |
| ISBN (print) | 9780819498564 |
| Publication status | Published - 2014 |
| Externally published | Yes |
Publication series
| Name | |
|---|---|
| Volume | 8943 |
| ISSN (Print) | 1605-7422 |
Conference
| Title | Photons Plus Ultrasound: Imaging and Sensing 2014 |
|---|---|
| Place | United States |
| City | San Francisco |
| Period | 2 - 5 February 2014 |
Link(s)
Abstract
Combined optical and mechanical scanning (COMS) in optical-resolution photoacoustic microscopy (OR-PAM) has provided five scanning modes with fast imaging speed and wide field of view (FOV). With two-dimensional (2D) galvanometer-based optical scanning, we have achieved a 2 KHz B-scan rate and 50 Hz volumetric-scan rate, which enables real-time tracking of cell activities in vivo. With optical-mechanical hybrid 2D scanning, we are able to image a wide FOV (10×8 mm2) within 150 seconds, which is 20 times faster than the conventional mechanical scan in our second-generation OR-PAM. With three-dimensional mechanical-based contour scanning, we can maintain the optimal signal-to-noise ratio and spatial resolution of OR-PAM while imaging objects with uneven surfaces, which is ideal for fast and quantitative studies of tumors and the brain. © 2014 SPIE.
Research Area(s)
- Medical and biological imaging, Photoacoustic imaging, Scanning microscopy, Three-dimensional microscopy
Citation Format(s)
Combined optical and mechanical scanning in optical-resolution photoacoustic microscopy. / Li, Lei; Yeh, Chenghung; Hu, Song et al.
Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8943 SPIE, 2014. 89435X.
Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8943 SPIE, 2014. 89435X.
Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review
