Chromosomal and plasmid-borne tigecycline resistance genes tet(X3) and tet(X4) in dairy cows in a Chinese farm
Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
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Detail(s)
Original language | English |
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Journal / Publication | Antimicrobial Agents and Chemotherapy |
Volume | 64 |
Issue number | 11 |
Online published | 17 Aug 2020 |
Publication status | Published - 20 Oct 2020 |
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Abstract
We isolated 47 Acinetobacter spp. carrying tet(X3) and 4 ST767 E. coli strains carrying tet(X4) from 296 rectal swab samples from dairy cows in a Chinese farm. tet(X3) was located on chromosomes or diverse plasmids, and tet(X4) was located on IncFIBκ/FIA(HI1)/X1 non-transferable plasmid. Co-existence of tet(X3) and carbapenemase genes including blaOXA-58 and blaNDM-1 were detected in 9 Acinetobacter spp. These findings suggested the use of tetracycline and other antibiotics in food production warrants urgent attention.
Research Area(s)
- Acinetobacter spp., dairy cow, E. coli, epidemiology, GI tract, tet(X3), tet(X4), tigecycline, WGS
Citation Format(s)
Chromosomal and plasmid-borne tigecycline resistance genes tet(X3) and tet(X4) in dairy cows in a Chinese farm. / Zhang, Rong; Dong, Ning; Zeng, Yu; Shen, Zhangqi; Lu, Jiauyue; Liu, Congcong; Huang, Zhuo-an; Sun, Qiaoling; Cheng, Qipeng; Shu, Lingbing; Cai, Jiachang; Waichi Chan, Edward; Liu, Dejun; Chen, Gongxiang; Wang, Yang; Chen, Sheng.
In: Antimicrobial Agents and Chemotherapy, Vol. 64, No. 11, 20.10.2020.Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review