CEST MRI of temporal changes of hematoma in Intracerebral Hemorrhage (ICH) mouse at 3T

Research output: Conference PapersAbstractpeer-review

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Detail(s)

Original languageEnglish
Publication statusPublished - May 2021

Conference

Title2021 International Society for Magnetic Resonance in Medicine (ISMRM) & Society for MR Radiographers & Technologists (SMRT) Annual Meeting
LocationOnline
Period15 - 20 May 2021

Abstract

CEST MRI in hematoma could be challenging depending on the involvement of iron. This study examined the feasibility of CEST in monitoring ICH and its progression over two weeks. The AREX data supported that the iron-overloading pathology might not significantly attenuate CEST contrast as demonstrated both in vitro and in vivo at 3T. We observed the most significant decrease in rNOE (37%) and APT (47%) contrast in lesions were onday7 and day3, respectively, when compared to contralateral side. This could indicate neuropathologies related to lipid and amide, which could be valuable for ICH diagnosis and treatment planning at 3T.

Citation Format(s)

CEST MRI of temporal changes of hematoma in Intracerebral Hemorrhage (ICH) mouse at 3T. / Lai, Joseph H. C.; Liu, Jiaxin; Huang, Jianpan et al.
2021. Abstract from 2021 International Society for Magnetic Resonance in Medicine (ISMRM) & Society for MR Radiographers & Technologists (SMRT) Annual Meeting.

Research output: Conference PapersAbstractpeer-review