Cell-Anchored Matrix Technology for High Throughput Single Cell Multidimensional Analysis

Ying XU; Chia-Hung CHEN

Cell-Anchored Matrix Technology for High Throughput Single Cell Multidimensional Analysis

Ying XU
, Chia-Hung CHEN^*

^*Corresponding author for this work

Department of Biomedical Engineering

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

Abstract

A cell-anchored matrix technology, cholesterol-linked antibody (CLAb), was developed for single-cell multidimensional analysis of cell types (surface biomarkers) and functionalities (secretions). Here, surface proteins (CD3, CD13) and secretions (IFN-γ, TNF-α) expressed by single immune cells (macrophages, dendritic cells) were simultaneously evaluated for immune profiling. Copyright © 2022 by the Chemical and Biological Microsystems Society.

Original language	English
Title of host publication	μTAS 2022 - The 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publisher	Chemical and Biological Microsystems Society
Pages	444-445
ISBN (Electronic)	9781733419048
Publication status	Published - Oct 2022
Event	26th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2022) - Hangzhou International Expo Center (Hybrid), Hangzhou, China Duration: 23 Oct 2022 → 27 Oct 2022 http://www.microtas2022.org https://www.cbmsociety.org/conference/proceedings_archive.html

Publication series

Name	MicroTAS - International Conference on Miniaturized Systems for Chemistry and Life Sciences
ISSN (Electronic)	1556-5904

Conference

Conference	26th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2022)
Place	China
City	Hangzhou
Period	23/10/22 → 27/10/22
Internet address	http://www.microtas2022.org https://www.cbmsociety.org/conference/proceedings_archive.html

Bibliographical note

Full text of this publication does not contain sufficient affiliation information. With consent from the author(s) concerned, the Research Unit(s) information for this record is based on the existing academic department affiliation of the author(s).

Research Keywords

Cell-anchored matrix
Cholesterol-linked antibody
High throughput single cell screen
Immune profiling
Multi-dimensional analysis

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XU, Y., & CHEN, C.-H. (2022). Cell-Anchored Matrix Technology for High Throughput Single Cell Multidimensional Analysis. In μTAS 2022 - The 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 444-445). (MicroTAS - International Conference on Miniaturized Systems for Chemistry and Life Sciences). Chemical and Biological Microsystems Society.

XU, Ying ; CHEN, Chia-Hung. / Cell-Anchored Matrix Technology for High Throughput Single Cell Multidimensional Analysis. μTAS 2022 - The 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2022. pp. 444-445 (MicroTAS - International Conference on Miniaturized Systems for Chemistry and Life Sciences).

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abstract = "A cell-anchored matrix technology, cholesterol-linked antibody (CLAb), was developed for single-cell multidimensional analysis of cell types (surface biomarkers) and functionalities (secretions). Here, surface proteins (CD3, CD13) and secretions (IFN-γ, TNF-α) expressed by single immune cells (macrophages, dendritic cells) were simultaneously evaluated for immune profiling. Copyright {\textcopyright} 2022 by the Chemical and Biological Microsystems Society.",

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XU, Y & CHEN, C-H 2022, Cell-Anchored Matrix Technology for High Throughput Single Cell Multidimensional Analysis. in μTAS 2022 - The 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences. MicroTAS - International Conference on Miniaturized Systems for Chemistry and Life Sciences, Chemical and Biological Microsystems Society, pp. 444-445, 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2022), Hangzhou, China, 23/10/22.

Cell-Anchored Matrix Technology for High Throughput Single Cell Multidimensional Analysis. / XU, Ying ; CHEN, Chia-Hung.
μTAS 2022 - The 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2022. p. 444-445 (MicroTAS - International Conference on Miniaturized Systems for Chemistry and Life Sciences).

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

TY - GEN

T1 - Cell-Anchored Matrix Technology for High Throughput Single Cell Multidimensional Analysis

AU - XU, Ying

AU - CHEN, Chia-Hung

N1 - Full text of this publication does not contain sufficient affiliation information. With consent from the author(s) concerned, the Research Unit(s) information for this record is based on the existing academic department affiliation of the author(s).

PY - 2022/10

Y1 - 2022/10

N2 - A cell-anchored matrix technology, cholesterol-linked antibody (CLAb), was developed for single-cell multidimensional analysis of cell types (surface biomarkers) and functionalities (secretions). Here, surface proteins (CD3, CD13) and secretions (IFN-γ, TNF-α) expressed by single immune cells (macrophages, dendritic cells) were simultaneously evaluated for immune profiling. Copyright © 2022 by the Chemical and Biological Microsystems Society.

AB - A cell-anchored matrix technology, cholesterol-linked antibody (CLAb), was developed for single-cell multidimensional analysis of cell types (surface biomarkers) and functionalities (secretions). Here, surface proteins (CD3, CD13) and secretions (IFN-γ, TNF-α) expressed by single immune cells (macrophages, dendritic cells) were simultaneously evaluated for immune profiling. Copyright © 2022 by the Chemical and Biological Microsystems Society.

KW - Cell-anchored matrix

KW - Cholesterol-linked antibody

KW - High throughput single cell screen

KW - Immune profiling

KW - Multi-dimensional analysis

UR - https://www.scopus.com/pages/publications/85175696891

UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-85175696891&origin=recordpage

M3 - RGC 32 - Refereed conference paper (with host publication)

T3 - MicroTAS - International Conference on Miniaturized Systems for Chemistry and Life Sciences

SP - 444

EP - 445

BT - μTAS 2022 - The 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences

PB - Chemical and Biological Microsystems Society

T2 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2022)

Y2 - 23 October 2022 through 27 October 2022

ER -

XU Y , CHEN CH. Cell-Anchored Matrix Technology for High Throughput Single Cell Multidimensional Analysis. In μTAS 2022 - The 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society. 2022. p. 444-445. (MicroTAS - International Conference on Miniaturized Systems for Chemistry and Life Sciences).

Cell-Anchored Matrix Technology for High Throughput Single Cell Multidimensional Analysis

Abstract

Publication series

Conference

Bibliographical note

Research Keywords

Other Access Options

Permanent Link

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