CARB-17 Family of β-Lactamases Mediates Intrinsic Resistance to Penicillins in Vibrio parahaemolyticus
Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Author(s)
Detail(s)
| Original language | English |
|---|---|
| Pages (from-to) | 3593-3595 |
| Journal / Publication | Antimicrobial Agents and Chemotherapy |
| Volume | 59 |
| Issue number | 6 |
| Online published | 14 May 2015 |
| Publication status | Published - 2015 |
| Externally published | Yes |
Link(s)
Abstract
Vibrio parahaemolyticus is commonly resistant to ampicillin, yet the mechanisms underlying this phenomenon are not clear. In this study, a novel class A carbenicillin-hydrolyzing β-lactamase (CARB) family of β-lactamases, blaCARB-17, was identified and found to be responsible for the intrinsic penicillin resistance in V. parahaemolyticus. Importantly, blaCARB-17-like genes were present in all 293 V. parahaemolyticus genome sequences available in GenBank and detectable in all 91 V. parahaemolyticus food isolates, further confirming the intrinsic nature of this gene.
Citation Format(s)
CARB-17 Family of β-Lactamases Mediates Intrinsic Resistance to Penicillins in Vibrio parahaemolyticus. / Chiou, Jiachi; Li, Ruichao; Chen, Sheng.
In: Antimicrobial Agents and Chemotherapy, Vol. 59, No. 6, 2015, p. 3593-3595.Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
