Abstract
In nature, organic molecules with great structural diversity and complexity are synthesized by utilizing a relatively small number of starting materials. A synthetic strategy adopted by nature is pathway branching, in which a common biosynthetic intermediate is transformed into different end products. A natural product can also be synthesized by the fusion of two or more precursors generated from separate metabolic pathways. This review article summarizes several representative branching and converging pathways in fungal natural product biosynthesis to illuminate how fungi are capable of synthesizing a diverse array of natural products.
| Original language | English |
|---|---|
| Article number | 6 |
| Journal | Fungal Biology and Biotechnology |
| Volume | 9 |
| Online published | 7 Mar 2022 |
| DOIs | |
| Publication status | Published - 2022 |
Funding
This work was in part supported by the Early Career Scheme grant from the Research Grants Council (RGC) of Hong Kong (Project No. 21300219 to Y.M.).
Research Keywords
- Natural products
- Biosynthesis
- Branching and converging pathways
Publisher's Copyright Statement
- This full text is made available under CC-BY 4.0. https://creativecommons.org/licenses/by/4.0/
RGC Funding Information
- RGC-funded
Fingerprint
Dive into the research topics of 'Branching and converging pathways in fungal natural product biosynthesis'. Together they form a unique fingerprint.Projects
- 1 Finished
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ECS: Comprehensive Understanding and Engineering of Fungal Xanthone Biosynthesis
MATSUDA, Y. (Principal Investigator / Project Coordinator)
1/01/20 → 13/12/23
Project: Research
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