Brachyspira aalborgi infection in four Australian children

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • RALF G HEINE
  • PETER B WARD
  • ANDREW SJ MIKOSZA
  • VICKI BENNETT-WOOD
  • ROY M ROBINS-BROWNE

Detail(s)

Original languageEnglish
Pages (from-to)872-875
Journal / PublicationJournal of Gastroenterology and Hepatology (Australia)
Volume16
Issue number8
Publication statusPublished - Aug 2001
Externally publishedYes

Abstract

Aim: The clinical presentation of four children and adolescents (two males and two females with a mean age of 12.4 years; range 9–16 years) with colorectal spirochetosis is discussed.

Results: Symptoms included persistent diarrhea (n = 2), rectal bleeding (n = 1) and abdominal pain (n = 2). In all patients, colorectal spirochetosis was an unanticipated finding on colonic histology, and the presence of spirochetes was confirmed by the use of electron microscopy. Spirochetes were identified as Brachyspira aalborgi by using PCR amplification of the bacterial 16S rRNA and nicotinamide adenine dinucleotide oxidase sequences in all four patients. No other enteric pathogens were found.

Conclusions: Although all patients appeared to respond to antibiotic treatment, the clinical significance of B. aalborgi as a human pathogen requires further investigation.

Research Area(s)

  • Abdominal pain, Brachyspira, Colon, Diarrhea, Spirochetosis

Citation Format(s)

Brachyspira aalborgi infection in four Australian children. / HEINE, RALF G; WARD, PETER B; MIKOSZA, ANDREW SJ et al.
In: Journal of Gastroenterology and Hepatology (Australia), Vol. 16, No. 8, 08.2001, p. 872-875.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review