TY - JOUR
T1 - Bioprospecting fungal-derived value-added bioproducts for sustainable pharmaceutical applications
AU - Afifa,
AU - Hussain, Nazim
AU - Baqar, Zulqarnain
AU - Mumtaz, Mehvish
AU - El-Sappah, Ahmed H.
AU - Show, Pau Loke
AU - Iqbal, Hafiz M.N.
AU - Varjani, Sunita
AU - Bilal, Muhammad
PY - 2022/10
Y1 - 2022/10
N2 - Fungi is a diverse group of microorganisms with over 1.5 million species worldwide. It lives in a variety of environments and develops a variety of survival mechanisms that allow it to manufacture a wide variety of chemicals, i.e., biomolecules. Organic acids, enzymes and secondary metabolites have been shown to be useful in the production of biomolecules. They may be used in a broad range of fields, including pharmaceutical research, agricultural and food biotechnology, commodities biochemicals, agri-foods, chemical engineering, diagnostics, medicines, and medical device development. It also explores fungal macromolecules' health and healing properties, regulates phytohormone synthesis or breakdown in plant roots, improves hormone production, and supports bio-stimulant composition. There are a variety of antimicrobial/antifungal biomolecules in agriculture that may be employed to minimize crop yield-reducing pest and diseases. These biomolecules, which are useful in both the pharmaceutical and agricultural industries, are the focus of this review. © 2022 Elsevier B.V. All rights reserved.
AB - Fungi is a diverse group of microorganisms with over 1.5 million species worldwide. It lives in a variety of environments and develops a variety of survival mechanisms that allow it to manufacture a wide variety of chemicals, i.e., biomolecules. Organic acids, enzymes and secondary metabolites have been shown to be useful in the production of biomolecules. They may be used in a broad range of fields, including pharmaceutical research, agricultural and food biotechnology, commodities biochemicals, agri-foods, chemical engineering, diagnostics, medicines, and medical device development. It also explores fungal macromolecules' health and healing properties, regulates phytohormone synthesis or breakdown in plant roots, improves hormone production, and supports bio-stimulant composition. There are a variety of antimicrobial/antifungal biomolecules in agriculture that may be employed to minimize crop yield-reducing pest and diseases. These biomolecules, which are useful in both the pharmaceutical and agricultural industries, are the focus of this review. © 2022 Elsevier B.V. All rights reserved.
KW - Antitumor activity
KW - Biological molecules
KW - Cardiovascular diseases
KW - Cytokinin
KW - Diabetes
KW - Fungal biomolecules
KW - Gibberellins
KW - Lipases
KW - Xylanases
UR - http://www.scopus.com/inward/record.url?scp=85132895759&partnerID=8YFLogxK
UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-85132895759&origin=recordpage
U2 - 10.1016/j.scp.2022.100755
DO - 10.1016/j.scp.2022.100755
M3 - RGC 21 - Publication in refereed journal
SN - 2352-5541
VL - 29
JO - Sustainable Chemistry and Pharmacy
JF - Sustainable Chemistry and Pharmacy
M1 - 100755
ER -
