Biomarker studies on gold-lined sea bream (Rhabdosargus sarba) exposed to benzo[a]pyrene

L. Xu; J. Chen; Y. Zhang; C. C C Cheung; P. K S Lam

Biomarker studies on gold-lined sea bream (Rhabdosargus sarba) exposed to benzo[a]pyrene

L. Xu, J. Chen, Y. Zhang, C. C C Cheung, P. K S Lam

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

Abstract

Gold-lined sea bream (Rhabdosargus sarba) were intraperitoneally injected with 35 mg/kg benzo[a]pyrene (in DMSO), with fish administered DMSO as the solvent control. Fish were sacrificed 3 days post injection and their livers dissected for the analysis of adenosine triphosphates (ATPase), glutathione-S-transferase (GST), DNA adducts and ethyoxyresorufin-O-deethylase (EROD). Exposure to B[a]P resulted in reduced ATPase activity, elevated GST activity and DNA adduct level, but no apparent change in EROD activity.

Original language	English
Pages (from-to)	155-160
Journal	Water Science and Technology
Volume	43
Issue number	2
Publication status	Published - 2001
Externally published	Yes

Research Keywords

ATPase
Benzo[a]pyrene
EROD
Gold-lined sea bream
GST, DNA adduct

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title = "Biomarker studies on gold-lined sea bream (Rhabdosargus sarba) exposed to benzo[a]pyrene",

abstract = "Gold-lined sea bream (Rhabdosargus sarba) were intraperitoneally injected with 35 mg/kg benzo[a]pyrene (in DMSO), with fish administered DMSO as the solvent control. Fish were sacrificed 3 days post injection and their livers dissected for the analysis of adenosine triphosphates (ATPase), glutathione-S-transferase (GST), DNA adducts and ethyoxyresorufin-O-deethylase (EROD). Exposure to B[a]P resulted in reduced ATPase activity, elevated GST activity and DNA adduct level, but no apparent change in EROD activity.",

keywords = "ATPase, Benzo[a]pyrene, EROD, Gold-lined sea bream, GST, DNA adduct",

author = "L. Xu and J. Chen and Y. Zhang and Cheung, {C. C C} and Lam, {P. K S}",

year = "2001",

language = "English",

volume = "43",

pages = "155--160",

journal = "Water Science and Technology",

issn = "0273-1223",

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number = "2",

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T1 - Biomarker studies on gold-lined sea bream (Rhabdosargus sarba) exposed to benzo[a]pyrene

AU - Xu, L.

AU - Chen, J.

AU - Zhang, Y.

AU - Cheung, C. C C

AU - Lam, P. K S

PY - 2001

Y1 - 2001

N2 - Gold-lined sea bream (Rhabdosargus sarba) were intraperitoneally injected with 35 mg/kg benzo[a]pyrene (in DMSO), with fish administered DMSO as the solvent control. Fish were sacrificed 3 days post injection and their livers dissected for the analysis of adenosine triphosphates (ATPase), glutathione-S-transferase (GST), DNA adducts and ethyoxyresorufin-O-deethylase (EROD). Exposure to B[a]P resulted in reduced ATPase activity, elevated GST activity and DNA adduct level, but no apparent change in EROD activity.

AB - Gold-lined sea bream (Rhabdosargus sarba) were intraperitoneally injected with 35 mg/kg benzo[a]pyrene (in DMSO), with fish administered DMSO as the solvent control. Fish were sacrificed 3 days post injection and their livers dissected for the analysis of adenosine triphosphates (ATPase), glutathione-S-transferase (GST), DNA adducts and ethyoxyresorufin-O-deethylase (EROD). Exposure to B[a]P resulted in reduced ATPase activity, elevated GST activity and DNA adduct level, but no apparent change in EROD activity.

KW - ATPase

KW - Benzo[a]pyrene

KW - EROD

KW - Gold-lined sea bream

KW - GST, DNA adduct

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UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-0035106458&origin=recordpage

M3 - RGC 21 - Publication in refereed journal

C2 - 11380174

SN - 0273-1223

VL - 43

SP - 155

EP - 160

JO - Water Science and Technology

JF - Water Science and Technology

IS - 2

ER -

Biomarker studies on gold-lined sea bream (Rhabdosargus sarba) exposed to benzo[a]pyrene

Abstract

Research Keywords

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