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Biointerface by cell growth on layered graphene-artificial peroxidase-protein nanostructure for in situ quantitative molecular detection

  • Chun Xian Guo
  • , Xin Ting Zheng
  • , Zhi Song Lu
  • , Xiong Wen Lou
  • , Chang Ming Li

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

Abstract

A smart multifunctional biointerface with dimensional compatibility and good electrical conductivity is constructed by growing human breast adenocarcinoma cells on layered graphene-artificial peroxidase-extracellular matrix protein and further used to in situ selectively and quantatively detect reactive oxygen species, for the first time discovering that the number of extracellular released hydrogen peroxide molecules is around 10<sup>11</sup> per cell. Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Original languageEnglish
Pages (from-to)5164-5167
JournalAdvanced Materials
Volume22
Issue number45
DOIs
Publication statusPublished - 1 Dec 2010
Externally publishedYes

Bibliographical note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

Funding

The authors gratefully acknowledge the financial support for the Center for Advanced Bionanosystems, Nanyang Technological University.

Research Keywords

  • biocompatible materials
  • biomedical applications
  • biosensors
  • layered materials
  • molecular recognition

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