Skip to main navigation Skip to search Skip to main content

Biodegradable freestanding rare-earth nanosheets promote multimodal imaging and delivers CRISPR-Cas9 plasmid against tumor

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

Abstract

Designing nanomaterials for bio-imaging and drug delivery for advanced cancer therapy with biodegradability and biocompatibility is a promising but challenging frontier. Herein, we assembled biodegradable and biocompatible ultrathin rare-earth erbium/dysprosium nanosheets that improve contrast in multimodal bio-imaging settings (MRI and X-ray CT) and deliver CRISPR-Cas9 plasmid to treat tumors. © The Royal Society of Chemistry 2021.
Original languageEnglish
Pages (from-to)9386-9389
JournalChemical Communications
Volume57
Issue number74
Online published10 Aug 2021
DOIs
Publication statusPublished - 21 Sept 2021
Externally publishedYes

Funding

We thank the National Key R&D Program of China (2018YFA0902600, 2017YFA0205901), the NSFC of China (21535001, 81730051, 21761142006) and the Chinese Academy of Science (QYZDJ-SSW-SLH039, 121D11KYSB20170026, XDA16020902), Tencent Foundation through the XPLORER PRIZE for the financial support. Shenzhen Key Laboratory of Smart Healthcare Engineering (ZDSYS20200811144003009).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Fingerprint

Dive into the research topics of 'Biodegradable freestanding rare-earth nanosheets promote multimodal imaging and delivers CRISPR-Cas9 plasmid against tumor'. Together they form a unique fingerprint.

Cite this