TY - JOUR
T1 - Biodegradable freestanding rare-earth nanosheets promote multimodal imaging and delivers CRISPR-Cas9 plasmid against tumor
AU - Balachandran, Yekkuni L.
AU - Li, Xuanyu
AU - Jiang, Xingyu
PY - 2021/9/21
Y1 - 2021/9/21
N2 - Designing nanomaterials for bio-imaging and drug delivery for advanced cancer therapy with biodegradability and biocompatibility is a promising but challenging frontier. Herein, we assembled biodegradable and biocompatible ultrathin rare-earth erbium/dysprosium nanosheets that improve contrast in multimodal bio-imaging settings (MRI and X-ray CT) and deliver CRISPR-Cas9 plasmid to treat tumors. © The Royal Society of Chemistry 2021.
AB - Designing nanomaterials for bio-imaging and drug delivery for advanced cancer therapy with biodegradability and biocompatibility is a promising but challenging frontier. Herein, we assembled biodegradable and biocompatible ultrathin rare-earth erbium/dysprosium nanosheets that improve contrast in multimodal bio-imaging settings (MRI and X-ray CT) and deliver CRISPR-Cas9 plasmid to treat tumors. © The Royal Society of Chemistry 2021.
UR - http://www.scopus.com/inward/record.url?scp=85115164521&partnerID=8YFLogxK
UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-85115164521&origin=recordpage
U2 - 10.1039/d1cc03228c
DO - 10.1039/d1cc03228c
M3 - RGC 21 - Publication in refereed journal
C2 - 34528946
SN - 1359-7345
VL - 57
SP - 9386
EP - 9389
JO - Chemical Communications
JF - Chemical Communications
IS - 74
ER -