Bioactive metabolites in functional and fermented foods and their role as immunity booster and anti-viral innate mechanisms

Kontham Kulangara Varsha, Vivek Narisetty, Kamalpreet Kaur Brar, Aravind Madhavan, Maria Paul Alphy, Raveendran Sindhu, Mukesh Kumar Awasthi, Sunita Varjani, Parameswaran Binod*

*Corresponding author for this work

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

17 Citations (Scopus)

Abstract

Live microorganisms in the fermented foods termed probiotics and their secondary metabolites with bioactive potential were considered as potential anti-viral capabilities through various mechanisms. Given the importance of functional and fermented foods in disease prevention, there is a need to discuss the contextualization and deep understanding of the mechanism of action of these foods, particularly considering the appearance of coronavirus (COVID-19) pandemic, which is causing health concerns and increased social services globally. The mechanism of probiotic strains or their bioactive metabolites is due to stimulation of immune response through boosting T-lymphocytes, cytokines, and cell toxicity of natural killer cells. Proper consumption of these functional and fermented foods may provide additional antiviral approaches for public benefit by modulating the immune functions in the hosts. © Association of Food Scientists & Technologists (India) 2022.
Original languageEnglish
Pages (from-to)2309–2318
JournalJournal of Food Science and Technology
Volume60
Issue number9
Online published24 Jun 2022
DOIs
Publication statusPublished - Sept 2023
Externally publishedYes

Research Keywords

  • Anti-viral metabolites
  • COVID-19
  • Fermented foods
  • Functional foods
  • Immunity

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