Bioactive compounds with anti-oxidative and anti-inflammatory activities of hop extracts
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
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Detail(s)
Original language | English |
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Article number | 127244 |
Number of pages | 8 |
Journal / Publication | Food Chemistry |
Volume | 330 |
Online published | 3 Jun 2020 |
Publication status | Published - 15 Nov 2020 |
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Abstract
The aim of this study is to simultaneously evaluate anti-oxidative and anti-inflammatory activities of the hop extracts by different solvents. Hop water extract (HWE) and hop ethanol extracts (HEEs) were prepared by extracting hop pellets with hot water at 90 °C and ethanol solutions (55%, 75%, and 95%), respectively. Bioactive compound such as α-acid, β-acid, total phenolic, and total flavonoid contents were determined. All the HEEs showed higher anti-oxidative activities than the HWEs. The HEEs showing the highest anti-oxidative activities are different in the experiments with different free radicals. For anti-inflammatory activities, both the HWE and HEEs decreased NO productions. HWE decreased TNF-α and IL-6 secretion but showed no effect on IL-1β, while HEEs decreased IL-1β and IL-6 secretion but increased TNF-α secretion. Except for TNF-α secretion, the HEEs showed higher anti-inflammatory activities than the HWE. Future work is to explore the possible mechanism to improve the ethanol extraction procedure.
Research Area(s)
- Hop, Humulus lupulus, Anti-oxidation, Anti-inflammation, Proinflammatory cytokine
Citation Format(s)
Bioactive compounds with anti-oxidative and anti-inflammatory activities of hop extracts. / Wu, Chun-Nan; Sun, Li-Chin; Chu, Yung-Lin et al.
In: Food Chemistry, Vol. 330, 127244, 15.11.2020.
In: Food Chemistry, Vol. 330, 127244, 15.11.2020.
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review