Bessel beam Grueneisen photoacoustic microscopy with extended depth of field

Research output: Chapters, Conference Papers, Creative and Literary WorksRGC 32 - Refereed conference paper (with host publication)peer-review

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Author(s)

Detail(s)

Original languageEnglish
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
PublisherSPIE
Volume9708
ISBN (Print)9781628419429
Publication statusPublished - 2016

Publication series

Name
Volume9708
ISSN (Print)1605-7422

Conference

TitlePhotons Plus Ultrasound: Imaging and Sensing 2016
PlaceUnited States
CitySan Francisco
Period14 - 17 February 2016

Abstract

The short focal depth of a Gaussian beam limits the volumetric imaging speed of optical resolution photoacoustic microscopy (OR-PAM). A Bessel beam, which is diffraction-free, provides a long focal depth, but its side-lobes may deteriorate image quality when the Bessel beam is directly employed to excite photoacoustic signals in ORPAM. Here, we present a nonlinear approach based on the Grueneisen relaxation effect to suppress the side-lobe artifacts in photoacoustic imaging. This method extends the focal depth of OR-PAM and speeds up volumetric imaging. We experimentally demonstrated a 1-mm focal depth with a 7-μm lateral resolution and volumetrically imaged a carbon fiber and red blood cell samples.

Research Area(s)

  • Bessel beam, Grueneisen relaxation, nonlinear microscopy, Photoacoustic

Citation Format(s)

Bessel beam Grueneisen photoacoustic microscopy with extended depth of field. / Shi, Junhui; Wang, Lidai; Noordam, Cedric et al.
Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 9708 SPIE, 2016. 97083H.

Research output: Chapters, Conference Papers, Creative and Literary WorksRGC 32 - Refereed conference paper (with host publication)peer-review