Axonal Fiber Terminations Concentrate on Gyri
Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Author(s)
Detail(s)
Original language | English |
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Pages (from-to) | 2831-2839 |
Journal / Publication | Cerebral Cortex |
Volume | 22 |
Issue number | 12 |
Online published | 20 Dec 2011 |
Publication status | Published - Dec 2012 |
Externally published | Yes |
Link(s)
Abstract
Convoluted cortical folding and neuronal wiring are 2 prominent attributes of the mammalian brain. However, the macroscale intrinsic relationship between these 2 general cross-species attributes, as well as the underlying principles that sculpt the architecture of the cerebral cortex, remains unclear. Here, we show that the axonal fibers connected to gyri are significantly denser than those connected to sulci. In human, chimpanzee, and macaque brains, a dominant fraction of axonal fibers were found to be connected to the gyri. This finding has been replicated in a range of mammalian brains via diffusion tensor imaging and high-angular resolution diffusion imaging. These results may have shed some lights on fundamental mechanisms for development and organization of the cerebral cortex, suggesting that axonal pushing is a mechanism of cortical folding.
Research Area(s)
- cortical folding, diffusion tensor imaging, shape analysis
Citation Format(s)
Axonal Fiber Terminations Concentrate on Gyri. / Nie, Jingxin; Guo, Lei; Li, Kaiming et al.
In: Cerebral Cortex, Vol. 22, No. 12, 12.2012, p. 2831-2839.Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review