Automated in-vivo transportation of biological cells with a robot-tweezers manipulation system

Xiaojian Li; Chichi Liu; Shuxun Chen; Yong Wang; S. H. Cheng; D. Sun

doi:10.1109/NANO.2015.7388719

Automated in-vivo transportation of biological cells with a robot-tweezers manipulation system

Xiaojian Li, Chichi Liu, Shuxun Chen, Yong Wang, S. H. Cheng, D. Sun^*

^*Corresponding author for this work

Department of Biomedical Sciences

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

9 Citations (Scopus)

Abstract

Robot-aided optical tweezers based manipulation tools have attracted increasing attention for advantages of trapping and manipulating micro/nano-scaled particles in biological environment. This paper presents a new research of using a robot-tweezers cell manipulation system to achieve in-vivo automated transportation of single red blood cells (RBCs). The position information of RBCs, extracted via image processing, is used as the feedback signal for the closed-loop tracking control. The experiment of transporting a single RBC in a living zebrafish demonstrates that such a closed-loop controlled robot-tweezers manipulation technology can transfer the cells precisely in vivo.

Original language	English
Title of host publication	IEEE-NANO 2015 - 15th International Conference on Nanotechnology
Publisher	IEEE
Pages	73-76
ISBN (Print)	9781467381550
DOIs	https://doi.org/10.1109/NANO.2015.7388719
Publication status	Published - Jul 2015
Event	15th IEEE International Conference on Nanotechnology, IEEE-NANO 2015 - Angelicum Congress Centre, Rome, Italy Duration: 27 Jul 2015 → 30 Jul 2015 http://www.ieeenano15.org/

Conference

Conference	15th IEEE International Conference on Nanotechnology, IEEE-NANO 2015
Place	Italy
City	Rome
Period	27/07/15 → 30/07/15
Internet address	http://www.ieeenano15.org/

Research Keywords

closed-loop control
in vivo cell manipulation
Optical tweezers

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10.1109/NANO.2015.7388719

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@inproceedings{22438fb21dbb4d6aad0b513eefb46273,

title = "Automated in-vivo transportation of biological cells with a robot-tweezers manipulation system",

abstract = "Robot-aided optical tweezers based manipulation tools have attracted increasing attention for advantages of trapping and manipulating micro/nano-scaled particles in biological environment. This paper presents a new research of using a robot-tweezers cell manipulation system to achieve in-vivo automated transportation of single red blood cells (RBCs). The position information of RBCs, extracted via image processing, is used as the feedback signal for the closed-loop tracking control. The experiment of transporting a single RBC in a living zebrafish demonstrates that such a closed-loop controlled robot-tweezers manipulation technology can transfer the cells precisely in vivo.",

keywords = "closed-loop control, in vivo cell manipulation, Optical tweezers",

author = "Xiaojian Li and Chichi Liu and Shuxun Chen and Yong Wang and Cheng, {S. H.} and D. Sun",

year = "2015",

month = jul,

doi = "10.1109/NANO.2015.7388719",

language = "English",

isbn = "9781467381550",

pages = "73--76",

booktitle = "IEEE-NANO 2015 - 15th International Conference on Nanotechnology",

publisher = "IEEE",

address = "United States",

note = "15th IEEE International Conference on Nanotechnology, IEEE-NANO 2015 ; Conference date: 27-07-2015 Through 30-07-2015",

url = "http://www.ieeenano15.org/",

}

Li, X, Liu, C, Chen, S, Wang, Y, Cheng, SH & Sun, D 2015, Automated in-vivo transportation of biological cells with a robot-tweezers manipulation system. in IEEE-NANO 2015 - 15th International Conference on Nanotechnology., 7388719, IEEE, pp. 73-76, 15th IEEE International Conference on Nanotechnology, IEEE-NANO 2015, Rome, Italy, 27/07/15. https://doi.org/10.1109/NANO.2015.7388719

Automated in-vivo transportation of biological cells with a robot-tweezers manipulation system. / Li, Xiaojian; Liu, Chichi; Chen, Shuxun et al.
IEEE-NANO 2015 - 15th International Conference on Nanotechnology. IEEE, 2015. p. 73-76 7388719.

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

TY - GEN

T1 - Automated in-vivo transportation of biological cells with a robot-tweezers manipulation system

AU - Li, Xiaojian

AU - Liu, Chichi

AU - Chen, Shuxun

AU - Wang, Yong

AU - Cheng, S. H.

AU - Sun, D.

PY - 2015/7

Y1 - 2015/7

N2 - Robot-aided optical tweezers based manipulation tools have attracted increasing attention for advantages of trapping and manipulating micro/nano-scaled particles in biological environment. This paper presents a new research of using a robot-tweezers cell manipulation system to achieve in-vivo automated transportation of single red blood cells (RBCs). The position information of RBCs, extracted via image processing, is used as the feedback signal for the closed-loop tracking control. The experiment of transporting a single RBC in a living zebrafish demonstrates that such a closed-loop controlled robot-tweezers manipulation technology can transfer the cells precisely in vivo.

AB - Robot-aided optical tweezers based manipulation tools have attracted increasing attention for advantages of trapping and manipulating micro/nano-scaled particles in biological environment. This paper presents a new research of using a robot-tweezers cell manipulation system to achieve in-vivo automated transportation of single red blood cells (RBCs). The position information of RBCs, extracted via image processing, is used as the feedback signal for the closed-loop tracking control. The experiment of transporting a single RBC in a living zebrafish demonstrates that such a closed-loop controlled robot-tweezers manipulation technology can transfer the cells precisely in vivo.

KW - closed-loop control

KW - in vivo cell manipulation

KW - Optical tweezers

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DO - 10.1109/NANO.2015.7388719

M3 - RGC 32 - Refereed conference paper (with host publication)

SN - 9781467381550

SP - 73

EP - 76

BT - IEEE-NANO 2015 - 15th International Conference on Nanotechnology

PB - IEEE

T2 - 15th IEEE International Conference on Nanotechnology, IEEE-NANO 2015

Y2 - 27 July 2015 through 30 July 2015

ER -

Automated in-vivo transportation of biological cells with a robot-tweezers manipulation system

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