Atranones with enhancement neurite outgrowth capacities from the crinoid-derived fungus stachybotrys chartarum 952

Yong-Fang Li; Pan-Pan Zhang; Su-Jun Yan; Jia-Yi Xu; Shah-Iram Niaz; Raza Chand; Chi Him Eddie Ma; Yong-Cheng Lin; Jing Li; Lan Liu

doi:10.1016/j.tet.2017.11.006

Author(s)

Yong-Fang Li
Pan-Pan Zhang
Su-Jun Yan
Jia-Yi Xu
Shah-Iram Niaz
Yong-Cheng Lin
Jing Li
Lan Liu

Related Research Unit(s)

Detail(s)

Original language	English
Pages (from-to)	7260-7266
Journal / Publication	Tetrahedron
Volume	73
Issue number	52
Online published	6 Nov 2017
Publication status	Published - 28 Dec 2017

Link(s)

DOI	DOI https://doi.org/10.1016/j.tet.2017.11.006 Final Published version
	Check@CityULib
Link to Scopus	https://www.scopus.com/record/display.uri?eid=2-s2.0-85035020700&origin=recordpage
Permanent Link	https://scholars.cityu.edu.hk/en/publications/publication(21e77bd6-7e24-4f76-8f1f-356a06ce39b9).html

Abstract

Seven new atranones (1–5, 7, 10) and three known analogues (6, 8, 9) were isolated from the marine crinoid-derived toxigenic fungus Stachybotrys chartarum 952. The structures of these compounds were elucidated by spectroscopic analysis as well as X-ray crystallographic analysis and electronic circular dichroism calculations. The absolute configurations of three known compounds 6, 8, 9 were first determined. Compound 8 promoted neurite outgrowth from adult DRG neurons significantly without affecting cell survival at 1 μg/mL concentrations.

Research Area(s)

Atranones, Crinoid, Stachybotrys chartarum

Citation Format(s)

[ RIS ] [ BibTeX ]

Atranones with enhancement neurite outgrowth capacities from the crinoid-derived fungus stachybotrys chartarum 952. / Li, Yong-Fang; Zhang, Pan-Pan; Yan, Su-Jun et al.
In: Tetrahedron, Vol. 73, No. 52, 28.12.2017, p. 7260-7266.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

Li, Y-F, Zhang, P-P, Yan, S-J, Xu, J-Y, Niaz, S-I, Chand, R , Eddie Ma, CH, Lin, Y-C, Li, J & Liu, L 2017, 'Atranones with enhancement neurite outgrowth capacities from the crinoid-derived fungus stachybotrys chartarum 952', Tetrahedron, vol. 73, no. 52, pp. 7260-7266. https://doi.org/10.1016/j.tet.2017.11.006

Li, Y.-F., Zhang, P.-P., Yan, S.-J., Xu, J.-Y., Niaz, S.-I., Chand, R., Eddie Ma, C. H., Lin, Y.-C., Li, J., & Liu, L. (2017). Atranones with enhancement neurite outgrowth capacities from the crinoid-derived fungus stachybotrys chartarum 952. Tetrahedron, 73(52), 7260-7266. https://doi.org/10.1016/j.tet.2017.11.006

Li YF, Zhang PP, Yan SJ, Xu JY, Niaz SI, Chand R et al. Atranones with enhancement neurite outgrowth capacities from the crinoid-derived fungus stachybotrys chartarum 952. Tetrahedron. 2017 Dec 28;73(52):7260-7266. Epub 2017 Nov 6. doi: 10.1016/j.tet.2017.11.006

Li, Yong-Fang ; Zhang, Pan-Pan ; Yan, Su-Jun et al. / Atranones with enhancement neurite outgrowth capacities from the crinoid-derived fungus stachybotrys chartarum 952. In: Tetrahedron. 2017 ; Vol. 73, No. 52. pp. 7260-7266.