Asymmetrical Titanium Oxide Patterns For Unidirectional Cell Guidance
Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review
Author(s)
Related Research Unit(s)
Detail(s)
| Original language | English |
|---|---|
| Title of host publication | 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. |
| Pages | 919-922 |
| ISBN (electronic) | 978-4-88686-435-2 |
| ISBN (print) | 979-8-3503-3302-2 |
| Publication status | Published - Jun 2023 |
Publication series
| Name | International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers |
|---|---|
| ISSN (Print) | 2167-0013 |
| ISSN (electronic) | 2167-0021 |
Conference
| Title | 22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 2023) |
|---|---|
| Location | Kyoto International Conference Center |
| Place | Japan |
| City | Kyoto |
| Period | 25 - 29 June 2023 |
Link(s)
| Document Link | Links
|
|---|---|
| Link to Scopus | https://www.scopus.com/record/display.uri?eid=2-s2.0-85193495410&origin=recordpage |
| Permanent Link | https://scholars.cityu.edu.hk/en/publications/publication(7c634911-172c-46e2-aabb-a84b8cc75d3f).html |
Abstract
Controlling the direction of cell migration is crucial for wound healing and tissue regeneration. To this end, polydimethylsiloxane (PDMS) platforms with a thin titanium oxide (TiOx with x=1.4) layer patterned in grating and arrowhead shapes were fabricated. In a novel approach, MC3T3-E1 cells seeded onto the platforms were confined to migrate over the patterned TiOx layer without physical barriers, instead of on the PDMS surface itself. Cells on a grating-shaped pattern were found to align with the grating orientation, exhibiting bidirectional migration. In comparison, the asymmetrical arrowheads of a patterned TiOx layer were able to guide cells along the tips of the arrowheads, which had larger contact areas. These findings suggest that biointerfaces with ultrathin patterns, such as the ones tested here, could offer better guidance over cell migration and inspire the development of new designs for biointerfaces. © 2023 IEEJ.
Research Area(s)
- Unidirectional Cell Migration, Patterned Titanium Oxide, Arrowhead Pattern, Grating, MC3T3-E1 Cell
Citation Format(s)
Asymmetrical Titanium Oxide Patterns For Unidirectional Cell Guidance. / Cheng, Yijun; Pang, Stella W.
2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers). Institute of Electrical and Electronics Engineers, Inc., 2023. p. 919-922 (International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers).
2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers). Institute of Electrical and Electronics Engineers, Inc., 2023. p. 919-922 (International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers).
Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review
