Antibacterial Activity of Silver Doped Titanate Nanowires on Ti Implants

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalNot applicablepeer-review

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Author(s)

  • Ziqiang Xu
  • Man Li
  • Xia Li
  • Xiangmei Liu
  • Fei Ma
  • Shuilin Wu
  • K. W. K. Yeung
  • Yong Han

Detail(s)

Original languageEnglish
Pages (from-to)16584-16594
Journal / PublicationACS Applied Materials and Interfaces
Volume8
Issue number26
Online published23 Jun 2016
Publication statusPublished - 6 Jul 2016

Abstract

A nanostructured film composed of one-dimensional titanate nanowires (TNWs) was employed as a carrier of Ag nanoparticles and chitosan (CS) to improve the surface antibacterial activity and biocompatibility of titanium implants. A TNWs film was produced on a Ti substrate by an alkali hydrothermal reaction and subsequently doped by Ag nanoparticles through an ultraviolet light chemical reduction. The CS nanofilm was deposited on the Ag nanoparticles through a spin-assisted layer by layer assembly method. The results disclosed that Ag nanoparticles were successfully carried by TNWs and homogeneously distributed on the entire surface. Moreover, a CS nanofilm was also successfully deposited on the Ag nanoparticles. Antibacterial tests showed that the samples modified with a higher initial concentration of AgNO3 solution exhibited better antibacterial activity, and that a CS nanofilm could further improve the antibacterial activity of the TNWs. Cell viability and ALP tests revealed that the release of Ag+ was detrimental for the growth, proliferation, and differentiation of MC3T3, and that CS could lower the negative effects of Ag gradually as the incubation time increased.

Research Area(s)

  • nanostructured film, nanowire, Ag nanoparticle, antibacterial, implant, titanium

Citation Format(s)

Antibacterial Activity of Silver Doped Titanate Nanowires on Ti Implants. / Xu, Ziqiang; Li, Man; Li, Xia; Liu, Xiangmei; Ma, Fei; Wu, Shuilin; Yeung, K. W. K.; Han, Yong; Chu, Paul K.

In: ACS Applied Materials and Interfaces, Vol. 8, No. 26, 06.07.2016, p. 16584-16594.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalNot applicablepeer-review