An ultra-sensitive and ratiometric fluorescent probe based on the DTBET process for Hg2+ detection and imaging applications

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

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Author(s)

  • Yin Jiang
  • Qinya Duan
  • Guansheng Zheng
  • Yafeng Wang
  • Huatang Zhang
  • Jun He

Detail(s)

Original languageEnglish
Pages (from-to)1353-1360
Journal / PublicationAnalyst
Volume144
Issue number4
Online published6 Dec 2018
Publication statusPublished - 21 Feb 2019

Abstract

In this article, we present an ultra-sensitive and ratiometric fluorescent probe (TR-Hg) for Hg2+ detection based on the mechanism of aggregation induced emission (AIE) and dark through-bond energy transfer (DTBET). The probe was constructed using tetraphenylethene as the dark donor and rhodamine B thiolactone as the acceptor. By exploiting the advantages of DTBET, which eliminates emission leakage from dark donors and provides nearly 100% energy transfer efficiency, TR-Hg exhibits more than a 30000-fold fluorescence ratio enhancement after reacting with Hg2+. TR-Hg demostrates (i) a detection limit of 43 pM, which is the lowest among the reported ratiometric Hg2+ probes, (ii) excellent selectivity, fast response-time (<10 s) and a wide pH application range, (iii) strong applicability for paper-based colorimetric assay, where readout can be performed by the naked eye, and (iv) fluorescent imaging of Hg2+ in onion epidermal tissues, indicating its potential use in living organisms.

Citation Format(s)

An ultra-sensitive and ratiometric fluorescent probe based on the DTBET process for Hg2+ detection and imaging applications. / Jiang, Yin; Duan, Qinya; Zheng, Guansheng; Yang, Liu; Zhang, Jie; Wang, Yafeng; Zhang, Huatang; He, Jun; Sun, Hongyan; Ho, Derek.

In: Analyst, Vol. 144, No. 4, 21.02.2019, p. 1353-1360.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal