An Enzymatic Electrochemical Biosensing Interface Developed by The Laser-Induced Graphene Electrode

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

View graph of relations

Author(s)

Related Research Unit(s)

Detail(s)

Original languageEnglish
Article number2300235
Journal / PublicationAdvanced Materials Interfaces
Volume10
Issue number35
Online published14 Sept 2023
Publication statusPublished - 13 Dec 2023

Link(s)

Abstract

Laser-inducing provides a cost-effective, easily-manufacturable, and environment-friendly approach to directly transfer carbon-rich polymers into graphene materials, which attracts attention from various fields, such as sensors, electrocatalysts, micro-supercapacitors, etc. Laser-induced graphene (LIG) benefits from the intrinsic properties of graphene, for example, high conductivity, high electroactivity, and high specific area. In this work the potential of laser-induced graphene in constructing an enzymatic electrochemical biosensing interface is evaluated. Here, a laminar-structured laser-induced graphene material is fabricated by laser engraving with polyimide. After deposition of the electron mediator ferrocene, a conjugated enzyme complex of bovine serum albumin-glucose oxidase (BSA-GOx) is modified on the laser-induced graphene by cross-linking. The fabricated glucose oxidase/ferrocene/LIG (GOx/Fc/LIG) biosensor achieves high sensitivity of 11.3 µA mM−1 cm−2), wide linear range of 0–11 mM, and low detection of limit of 0.04 µM. The LIG electrodes exhibit high flexibility with bending angle as high as 60° without observed conductivity change. The repeatability and robustness of the developed LIG biosensor in detection of real serum samples empower it with great potential in clinical implementation in the future. © 2023 The Authors. Advanced Materials Interfaces published by Wiley-VCH GmbH.

Research Area(s)

  • electrochemical biosensors, enzymatic biosensors, laser-induced graphene, sensing interface

Citation Format(s)

An Enzymatic Electrochemical Biosensing Interface Developed by The Laser-Induced Graphene Electrode. / Liu, Mingyang; Zhao, Guangyao; Yang, Cheng et al.
In: Advanced Materials Interfaces, Vol. 10, No. 35, 2300235, 13.12.2023.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

Download Statistics

No data available