An antibacterial platform based on capacitive carbon-doped TiO2 nanotubes after charging with direct/alternating currents

Research output: Conference Papers (RGC: 31A, 31B, 32, 33)32_Refereed conference paper (no ISBN/ISSN)peer-review

View graph of relations

Author(s)

Detail(s)

Original languageEnglish
Publication statusPublished - May 2019

Conference

Title37th Spring Meeting of the European Materials Research Society (E-MRS 2019)
PlaceFrance
CityNice
Period27 - 31 May 2019

Abstract

Electrical interactions between bacteria and the environment are delicate and essential [1][2]. For instance, by means of electron transfer, bacteria complete respiration on the cell membrane to supply energy for cell growth, proliferation, and maintenance and disturbing electron transfer in bacteria can raise the production of reactive oxygen species (ROS) to hinder growth. In this study [3], an external electrical current is applied to capacitive titania nanotubes doped with carbon (TNT-C) to evaluate the effects on bacteria killing and the underlying mechanism is investigated. When TNT-C is charged, post-charging antibacterial effects proportional to the capacitance are observed. This capacitance-based antibacterial system works well with both direct and alternating current (DC, AC) and the higher discharging capacity in the positive DC (DC ) group leads to better antibacterial performance. Extracellular electron transfer observed during early contact contributes to the surface-dependent post-charging antibacterial process. Physiologically, the electrical interaction deforms the bacteria morphology and elevates the intracellular reactive oxygen species level without impairing the growth of osteoblasts. This is the first systematic study on the post-charging antibacterial properties of biomaterials with tunable capacitance. Our finding spurs the design of light-independent antibacterial materials and provides insights into the use of electricity to modify biomaterials to complement other bacteria killing measures such as light irradiation. References [1] G. M. Wang, H. Q. Feng, et al. ACS Applied Materials and Interfaces, vol. 8, no. 37, pp. 24509 ? 24516 (2016). [2] G. M. Wang, W. H. Jin, et al. Biomaterials, vol. 124, pp. 25 ? 34 (2017). [3] G. M. Wang, H. Q. Feng, et al. Nature Communications, vol. 9, Paper 2055 (2018).

Citation Format(s)

An antibacterial platform based on capacitive carbon-doped TiO2 nanotubes after charging with direct/alternating currents. / Wang, Guomin; Wang, Huaiyu; Chu, Paul K.

2019. Paper presented at 37th Spring Meeting of the European Materials Research Society (E-MRS 2019), Nice, France.

Research output: Conference Papers (RGC: 31A, 31B, 32, 33)32_Refereed conference paper (no ISBN/ISSN)peer-review