An activity-based fluorescent probe and its application for differentiating alkaline phosphatase activity in different cell lines
Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
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Detail(s)
Original language | English |
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Pages (from-to) | 13323-13326 |
Journal / Publication | Chemical Communications |
Volume | 56 |
Issue number | 87 |
Online published | 30 Sep 2020 |
Publication status | Published - 11 Nov 2020 |
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Abstract
Herein, a new fluorescent probe, AE-Phos, is reported for detecting the ALP activity with the combined advantages of aggregation-induced emission (AIE) and excited state intramolecular proton transfer (ESIPT). Further detailed fluorescence experiments demonstrated that AE-Phos exhibited excellent selectivity and sensitivity, a large Stokes shift, and a fast response towards ALP. Furthermore, AE-Phos was applied to imaging the ALP activity in different cell lines quantitatively. This journal is
Citation Format(s)
An activity-based fluorescent probe and its application for differentiating alkaline phosphatase activity in different cell lines. / He, Yong; Yu, Junli; Hu, Xiangzi et al.
In: Chemical Communications, Vol. 56, No. 87, 11.11.2020, p. 13323-13326.Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review