Akt-ing Up on SRPK1: Oncogene or Tumor Suppressor?

Alex Toker; Y. Rebecca Chin

doi:10.1016/j.molcel.2014.04.020

Akt-ing Up on SRPK1: Oncogene or Tumor Suppressor?

Alex Toker^*
, Y. Rebecca Chin^*

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 62 - Review of books or of software (or similar publications/items) › peer-review

14 Citations (Scopus)

Abstract

In this issue of Molecular Cell, Wang et al. (2014) report that the splicing kinase SRPK1 can function as both an oncogene and a tumor suppressor by modulating the activation state of the protein kinase Akt. This is shown to be mediated by the ability of SRPK1 to bind to the Akt phosphatase PHLPP1.

Original language	English
Pages (from-to)	329-330
Journal	Molecular Cell
Volume	54
Issue number	3
DOIs	https://doi.org/10.1016/j.molcel.2014.04.020
Publication status	Published - 8 May 2014
Externally published	Yes

Access Output

10.1016/j.molcel.2014.04.020Licence: Elsevier user license

Other Access Options

Check CityUHK Library

Permanent Link

Right click to copy link

Cite this

@article{d7afbab18c5949fea96a2372264328dc,

title = "Akt-ing Up on SRPK1: Oncogene or Tumor Suppressor?",

abstract = "In this issue of Molecular Cell, Wang et al. (2014) report that the splicing kinase SRPK1 can function as both an oncogene and a tumor suppressor by modulating the activation state of the protein kinase Akt. This is shown to be mediated by the ability of SRPK1 to bind to the Akt phosphatase PHLPP1.",

author = "Alex Toker and Chin, \{Y. Rebecca\}",

year = "2014",

month = may,

day = "8",

doi = "10.1016/j.molcel.2014.04.020",

language = "English",

volume = "54",

pages = "329--330",

journal = "Molecular Cell",

issn = "1097-2765",

publisher = "Cell Press",

number = "3",

}

TY - JOUR

T1 - Akt-ing Up on SRPK1

T2 - Oncogene or Tumor Suppressor?

AU - Toker, Alex

AU - Chin, Y. Rebecca

PY - 2014/5/8

Y1 - 2014/5/8

N2 - In this issue of Molecular Cell, Wang et al. (2014) report that the splicing kinase SRPK1 can function as both an oncogene and a tumor suppressor by modulating the activation state of the protein kinase Akt. This is shown to be mediated by the ability of SRPK1 to bind to the Akt phosphatase PHLPP1.

AB - In this issue of Molecular Cell, Wang et al. (2014) report that the splicing kinase SRPK1 can function as both an oncogene and a tumor suppressor by modulating the activation state of the protein kinase Akt. This is shown to be mediated by the ability of SRPK1 to bind to the Akt phosphatase PHLPP1.

UR - https://www.scopus.com/pages/publications/84899790149

UR - https://www.scopus.com/pages/publications/84899790149#tab=impact

U2 - 10.1016/j.molcel.2014.04.020

DO - 10.1016/j.molcel.2014.04.020

M3 - RGC 62 - Review of books or of software (or similar publications/items)

C2 - 24813709

SN - 1097-2765

VL - 54

SP - 329

EP - 330

JO - Molecular Cell

JF - Molecular Cell

IS - 3

ER -

Akt-ing Up on SRPK1: Oncogene or Tumor Suppressor?

Abstract

Access Output

Other Access Options

Permanent Link

Other Files and Links

Fingerprint

Cite this