TY - JOUR
T1 - Ag nanoparticles
T2 - Size- and surface-dependent effects on model aquatic organisms and uptake evaluation with NanoSIMS
AU - Georgantzopoulou, Anastasia
AU - Balachandran, Yekkuni L.
AU - Rosenkranz, Philipp
AU - Dusinska, Maria
AU - Lankoff, Anna
AU - Wojewodzka, Maria
AU - Kruszewski, Marcin
AU - Guignard, Cédric
AU - Audinot, Jean-Nicolas
AU - Girija, Shanmugam
AU - Hoffmann, Lucien
AU - Gutleb, Arno C.
N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].
PY - 2013/11
Y1 - 2013/11
N2 - This study aims to assess the effects of Ag particles synthesised by a chemical (Ag 20, 200 nm) and biological method (Ag 23, 27 nm) in aquatic organisms: the bacterium Vibrio fischeri, the alga Desmodesmus subspicatus and the crustacean Daphnia magna. Ag particles exerted toxic effects in all organisms studied with Ag particles 23 nm being the most potent. Although soluble Ag was released in all media, the differences between the tested Ag particles still cannot be explained solely based on soluble Ag. NanoSIMS analysis performed with D. magna showed that apart from their localisation in the gut lumen, Ag 200 nm and Ag NPs 23 nm seemed to pass through the epithelial barrier as well. Ag NPs 23 nm localised in specific areas seemed to be within the ovaries. This study strengthens the argument that size, method of synthesis as well as surface chemistry may affect the uptake and toxic effects of Ag NPs. © Informa UK, Ltd.
AB - This study aims to assess the effects of Ag particles synthesised by a chemical (Ag 20, 200 nm) and biological method (Ag 23, 27 nm) in aquatic organisms: the bacterium Vibrio fischeri, the alga Desmodesmus subspicatus and the crustacean Daphnia magna. Ag particles exerted toxic effects in all organisms studied with Ag particles 23 nm being the most potent. Although soluble Ag was released in all media, the differences between the tested Ag particles still cannot be explained solely based on soluble Ag. NanoSIMS analysis performed with D. magna showed that apart from their localisation in the gut lumen, Ag 200 nm and Ag NPs 23 nm seemed to pass through the epithelial barrier as well. Ag NPs 23 nm localised in specific areas seemed to be within the ovaries. This study strengthens the argument that size, method of synthesis as well as surface chemistry may affect the uptake and toxic effects of Ag NPs. © Informa UK, Ltd.
KW - Ag nanoparticles
KW - Daphnia magna
KW - Desmodesmus subspicatus
KW - NanoSIMS
KW - Vibrio fischeri
UR - http://www.scopus.com/inward/record.url?scp=84883341787&partnerID=8YFLogxK
UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-84883341787&origin=recordpage
U2 - 10.3109/17435390.2012.715312
DO - 10.3109/17435390.2012.715312
M3 - RGC 21 - Publication in refereed journal
C2 - 22834480
SN - 1743-5390
VL - 7
SP - 1168
EP - 1178
JO - Nanotoxicology
JF - Nanotoxicology
IS - 7
ER -