Advances in the Formulations of Microneedles for Manifold Biomedical Applications

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Hao Chang
  • Mengjia Zheng
  • Sharon Wan Ting Chew
  • Chenjie Xu

Related Research Unit(s)

Detail(s)

Original languageEnglish
Article number1900552
Journal / PublicationAdvanced Materials Technologies
Volume5
Issue number4
Online published24 Jan 2020
Publication statusPublished - Apr 2020

Abstract

Transdermal delivery systems have recently attracted a great interest due to its minimal invasiveness and convenience. One latest technology in this field is the microneedle technology, which is a single or array of miniaturized needles on the micrometer scale. They pierce the stratum corneum and create transient microchannels for drug diffusion or extraction of skin interstitial fluid. The latest developments of the microneedles are reviewed here by focusing on the materials and fabrication techniques. They are categorized into nonpolymeric and polymeric ones that are made through a wide range of technologies such as lithography, micromolding, droplet-born air blowing. Powered by the unique structures and functional materials, these microneedle platforms can provide solutions for skin diseases, diabetes, obesity, ocular diseases, as well as point-of-care diagnosis.

Research Area(s)

  • microneedles, ocular delivery, transdermal diagnosis, transdermal drug delivery

Citation Format(s)

Advances in the Formulations of Microneedles for Manifold Biomedical Applications. / Chang, Hao; Zheng, Mengjia; Chew, Sharon Wan Ting et al.

In: Advanced Materials Technologies, Vol. 5, No. 4, 1900552, 04.2020.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review