Adsorption and desorption behaviors of selected endocrine disrupting chemicals in simulated gastrointestinal fluids

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

10 Scopus Citations
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Author(s)

Detail(s)

Original languageEnglish
Pages (from-to)363-369
Journal / PublicationMarine Pollution Bulletin
Volume85
Issue number2
Online published15 Jan 2014
Publication statusPublished - 30 Aug 2014
Externally publishedYes

Abstract

An in vitro technique using simulated gastrointestinal (GI) fluids was applied to investigate the desorption of selected endocrine disrupting chemicals (EDCs), i.e. bisphenol A (BPA) and 17 α-ethinylestradiol (EE2), from the marine sediment in the digestive environment. The results show that the GI fluids suppressed chemical adsorption and greatly increased the desorption of BPA and EE2 from the sediment. Pepsin in the gastric fluid would compete for the adsorption sites with the adsorbates, and bile salts in the intestinal fluid had a solubilization effect on the chemicals. The amount of chemical release from the sediment in different fluids followed intestinal (fed) > intestinal (fasted) > gastric > saline water. During the dynamic desorption tests, 62% and 21% of sediment-bound BPA and EE2, respectively, could be released into the simulated GI fluids. The enhanced desorption of EDCs from sediment in the digestive system would make the pollutants more bioavailable in the ecosystem. © 2014 Elsevier Ltd.

Research Area(s)

  • 17 α-Ethinylestradiol (EE2), Adsorption, Bisphenol A (BPA), Desorption, Gastrointestinal fluids, Marine sediment