TY - GEN
T1 - Active manipulation of ECM stiffness
AU - Chen, Peter C.Y.
AU - Herath, Sahan C.B.
AU - Wang, Dong-an
AU - Su, Kai
AU - Liao, Kin
AU - Asada, Harry
PY - 2011/6
Y1 - 2011/6
N2 - The mechanical properties of the microstructures surrounding cells influence the behavior of cells in differentiation, proliferation, and apoptosis, etc. The stiffness of the extra-cellular microenvironment has been shown to be one such mechanical property [1][2]. Studies reported in the literature concerning the stiffness of the extracellular microenvironment mainly sought to understand the scientific principles and mechanisms underlying its effect on cell-environment interaction [3]. This paper describes an approach that achieves such manipulation, and reports experimental results that demonstrate the effectiveness of this proposed approach.
AB - The mechanical properties of the microstructures surrounding cells influence the behavior of cells in differentiation, proliferation, and apoptosis, etc. The stiffness of the extra-cellular microenvironment has been shown to be one such mechanical property [1][2]. Studies reported in the literature concerning the stiffness of the extracellular microenvironment mainly sought to understand the scientific principles and mechanisms underlying its effect on cell-environment interaction [3]. This paper describes an approach that achieves such manipulation, and reports experimental results that demonstrate the effectiveness of this proposed approach.
UR - http://www.scopus.com/inward/record.url?scp=84881225772&partnerID=8YFLogxK
UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-84881225772&origin=recordpage
U2 - 10.1115/SBC2011-53090
DO - 10.1115/SBC2011-53090
M3 - RGC 32 - Refereed conference paper (with host publication)
T3 - ASME Summer Bioengineering Conference, SBC
SP - 869
EP - 870
BT - ASME 2011 Summer Bioengineering Conference
PB - American Society of Mechanical Engineers
T2 - ASME 2011 Summer Bioengineering Conference (SBC 2011)
Y2 - 22 June 2011 through 25 June 2011
ER -