Activation, Permeability, and Inhibition of Astrocytic and Neuronal Large Pore (Hemi)channels

Daniel Bloch Hansen; Zu-Cheng Ye; Kirstine Calloe; Thomas Hartig Braunstein; Johannes Pauli Hofgaard; Bruce R. Ransom; Morten Schak Nielsen; Nanna MacAulay

doi:10.1074/jbc.M114.582155

Author(s)

Daniel Bloch Hansen
Zu-Cheng Ye
Kirstine Calloe
Thomas Hartig Braunstein
Johannes Pauli Hofgaard
Morten Schak Nielsen
Nanna MacAulay

Detail(s)

Original language	English
Pages (from-to)	26058-26073
Journal / Publication	Journal of Biological Chemistry
Volume	289
Issue number	38
Online published	1 Aug 2014
Publication status	Published - 19 Sept 2014
Externally published	Yes

Link(s)

DOI	DOI https://doi.org/10.1074/jbc.M114.582155 Final Published version
	Check@CityULib
Attachment(s)	Documents 41913210.pdf Final Published version, 2.03 MB, PDF Publisher's Copyright Statement This full text is made available under CC-BY 4.0. https://creativecommons.org/licenses/by/4.0/
Link to Scopus	https://www.scopus.com/record/display.uri?eid=2-s2.0-84907200743&origin=recordpage
Permanent Link	https://scholars.cityu.edu.hk/en/publications/publication(268c218d-4f3b-44cd-a2ac-1a85ea09f574).html

Abstract

Background: The permeability and physiological role of several large pore (hemi)channels are unresolved.
Results: Large pore (hemi)channels, when heterologously expressed, display isoform-specific permeability and gating for ionsand fluorescent dyes.
Conclusion: Large pore channels have isoform-specific transport characteristics that can be used for their identification.
Significance: Although large pore channels have characteristic properties in overexpression systems, these properties may beundetectable in native cells.

Research Area(s)

Citation Format(s)

[ RIS ] [ BibTeX ]

Activation, Permeability, and Inhibition of Astrocytic and Neuronal Large Pore (Hemi)channels. / Hansen, Daniel Bloch; Ye, Zu-Cheng; Calloe, Kirstine et al.
In: Journal of Biological Chemistry, Vol. 289, No. 38, 19.09.2014, p. 26058-26073.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

Hansen, DB, Ye, Z-C, Calloe, K, Braunstein, TH, Hofgaard, JP, Ransom, BR, Nielsen, MS & MacAulay, N 2014, 'Activation, Permeability, and Inhibition of Astrocytic and Neuronal Large Pore (Hemi)channels', Journal of Biological Chemistry, vol. 289, no. 38, pp. 26058-26073. https://doi.org/10.1074/jbc.M114.582155

Hansen, D. B., Ye, Z.-C., Calloe, K., Braunstein, T. H., Hofgaard, J. P., Ransom, B. R., Nielsen, M. S., & MacAulay, N. (2014). Activation, Permeability, and Inhibition of Astrocytic and Neuronal Large Pore (Hemi)channels. Journal of Biological Chemistry, 289(38), 26058-26073. https://doi.org/10.1074/jbc.M114.582155

Hansen DB, Ye ZC, Calloe K, Braunstein TH, Hofgaard JP, Ransom BR et al. Activation, Permeability, and Inhibition of Astrocytic and Neuronal Large Pore (Hemi)channels. Journal of Biological Chemistry. 2014 Sept 19;289(38):26058-26073. Epub 2014 Aug 1. doi: 10.1074/jbc.M114.582155

Hansen, Daniel Bloch ; Ye, Zu-Cheng ; Calloe, Kirstine et al. / Activation, Permeability, and Inhibition of Astrocytic and Neuronal Large Pore (Hemi)channels. In: Journal of Biological Chemistry. 2014 ; Vol. 289, No. 38. pp. 26058-26073.

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