Achieving vinylic selectivity in Mizoroki-heck reaction of cyclic olefins

Xiaojin Wu, Yunpeng Lu, Hajime Hirao, Jianrong Zhou*

*Corresponding author for this work

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

17 Citations (Scopus)

Abstract

In Heck reactions of cyclic olefins, the products usually have aryl groups that end up at the allylic and/or homoallylic position. We herein report new selectivity that adds aryl groups to the vinylic position. Cyclic olefins of various ring size worked well. The desired isomers were produced by palladium-hydride-catalyzed isomerization of the initial products. Thus, a specific catalyst must be used so that it can perform two jobs under one set of reaction conditions. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Original languageEnglish
Pages (from-to)6014-6020
JournalChemistry - A European Journal
Volume19
Issue number19
DOIs
Publication statusPublished - 3 May 2013
Externally publishedYes

Research Keywords

  • arylation
  • Heck reaction
  • isomerization
  • olefins
  • vinylic selectivity

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