A two-photon fluorescent probe for sensitive detection and imaging of γ-glutamyl transpeptidase

Ruijin Huo; Xiuli Zheng; Weimin Liu; Liping Zhang; Jiasheng Wu; Fan Li; Wenjun Zhang; Chun-Sing Lee; Pengfei Wang

doi:10.1039/d0cc02750b

A two-photon fluorescent probe for sensitive detection and imaging of γ-glutamyl transpeptidase

Ruijin Huo, Xiuli Zheng, Weimin Liu^*, Liping Zhang, Jiasheng Wu, Fan Li, Wenjun Zhang, Chun-Sing Lee, Pengfei Wang

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

36 Citations (Scopus)

Abstract

A GGT-activated two-photon fluorescent probe (4F-2CN-GSH) was developed based on a cascade reaction. 4F-2CN-GSH could selectivily detect GGT with low detection limit and distinguish ovarian cancer cells from normal cells using both one-photon and two-photon fluorescence imaging.

Original language	English
Pages (from-to)	10902-10905
Journal	Chemical Communications
Volume	56
Issue number	74
Online published	5 Aug 2020
DOIs	https://doi.org/10.1039/d0cc02750b
Publication status	Published - 21 Sept 2020

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title = "A two-photon fluorescent probe for sensitive detection and imaging of γ-glutamyl transpeptidase",

abstract = "A GGT-activated two-photon fluorescent probe (4F-2CN-GSH) was developed based on a cascade reaction. 4F-2CN-GSH could selectivily detect GGT with low detection limit and distinguish ovarian cancer cells from normal cells using both one-photon and two-photon fluorescence imaging.",

author = "Ruijin Huo and Xiuli Zheng and Weimin Liu and Liping Zhang and Jiasheng Wu and Fan Li and Wenjun Zhang and Chun-Sing Lee and Pengfei Wang",

year = "2020",

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doi = "10.1039/d0cc02750b",

language = "English",

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journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - A two-photon fluorescent probe for sensitive detection and imaging of γ-glutamyl transpeptidase

AU - Huo, Ruijin

AU - Zheng, Xiuli

AU - Liu, Weimin

AU - Zhang, Liping

AU - Wu, Jiasheng

AU - Li, Fan

AU - Zhang, Wenjun

AU - Lee, Chun-Sing

AU - Wang, Pengfei

PY - 2020/9/21

Y1 - 2020/9/21

N2 - A GGT-activated two-photon fluorescent probe (4F-2CN-GSH) was developed based on a cascade reaction. 4F-2CN-GSH could selectivily detect GGT with low detection limit and distinguish ovarian cancer cells from normal cells using both one-photon and two-photon fluorescence imaging.

AB - A GGT-activated two-photon fluorescent probe (4F-2CN-GSH) was developed based on a cascade reaction. 4F-2CN-GSH could selectivily detect GGT with low detection limit and distinguish ovarian cancer cells from normal cells using both one-photon and two-photon fluorescence imaging.

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UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-85091191374&origin=recordpage

U2 - 10.1039/d0cc02750b

DO - 10.1039/d0cc02750b

M3 - RGC 21 - Publication in refereed journal

C2 - 32808621

SN - 1359-7345

VL - 56

SP - 10902

EP - 10905

JO - Chemical Communications

JF - Chemical Communications

IS - 74

ER -

A two-photon fluorescent probe for sensitive detection and imaging of γ-glutamyl transpeptidase

Abstract

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