A transmission electron microscopy study of mineralization in age-induced transparent dentin

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

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Author(s)

  • Alexandra E. Porter
  • Ravi K. Nalla
  • Andrew Minor
  • Joerg R. Jinschek
  • Christian Kisielowski
  • Velimir Radmilovic
  • John H. Kinney
  • Antoni P. Tomsia

Detail(s)

Original languageEnglish
Pages (from-to)7650-7660
Journal / PublicationBiomaterials
Volume26
Issue number36
Online published11 Jul 2005
Publication statusPublished - Dec 2005
Externally publishedYes

Abstract

It is known that fractures are more likely to occur in altered teeth, particularly following restoration or endodontic repair; consequently, it is important to understand the structure of altered forms of dentin, the most abundant tissue in the human tooth, in order to better define the increased propensity for such fractures. Transparent (or sclerotic) dentin, wherein the dentinal tubules become occluded with mineral as a natural progressive consequence of aging, is one such altered form. In the present study, high-resolution transmission electron microscopy is used to investigate the effect of aging on the mineral phase of dentin. Such studies revealed that the intertubular mineral crystallites were smaller in transparent dentin, and that the intratubular mineral (larger crystals deposited within the tubules) was chemically similar to the surrounding intertubular mineral. Exit-wave reconstructed lattice-plane images suggested that the intratubular mineral had nanometer-size grains. These observations support a "dissolution and reprecipitation" mechanism for the formation of transparent dentin.

Research Area(s)

  • Aging, Dentin, Mineralization, Sclerotic, Transmission electron microscopy, Transparent

Citation Format(s)

A transmission electron microscopy study of mineralization in age-induced transparent dentin. / Porter, Alexandra E.; Nalla, Ravi K.; Minor, Andrew; Jinschek, Joerg R.; Kisielowski, Christian; Radmilovic, Velimir; Kinney, John H.; Tomsia, Antoni P.; Ritchie, R. O.

In: Biomaterials, Vol. 26, No. 36, 12.2005, p. 7650-7660.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal