A theoretical analysis of neural firing rate function based on an integral pulse frequency modulation model

Y. Y. Gu, Y. T. Zhang, T. Ma

Research output: Chapters, Conference Papers, Creative and Literary WorksRGC 32 - Refereed conference paper (with host publication)peer-review

1 Citation (Scopus)

Abstract

Lon-pass filtering techniques have been suggested as a simple approach lo recover the original input modulating information from an integral pulse frequency modulation (IPFM) process mimicking neural physiological encoding mechanisms, However, due to the non-linearity of the IPFM model and the difficulty in estimating the threshold value of neurons in vivo, it is practically implausible to recoYer precisely the input modulation amplitude or intensity information through simple low-pass filtering. Instead, it is found through a mathematical analysis that such demodulation is of special importance for studying the firing characteristia of neural and muscle cells. In this paper, with a single sinusoidal signal as the input modulation signal lo the IPFM model, an expression for the relationship between the instantaneous firing rate and the intensity of input signals is derived. The results show that the firing rate function in terms of the modulating signal and the threshold can be reconstructed mth reasonable accuracy by simple low-pass filtering.
Original languageEnglish
Title of host publicationIEEE EMBS APBME2003
Subtitle of host publicationIEEE EMBS Asian-Pacific Conference on Biomedical Engineering 2003
PublisherIEEE
Pages144-145
ISBN (Print)0-7803-7943-8
DOIs
Publication statusPublished - Oct 2003
Externally publishedYes
EventIEEE EMBS Asian-Pacific Conference on Biomedical Engineering 2003 (IEEE EMBS APBME2003) - Kyoto-Osaka-Nara, Japan
Duration: 20 Oct 200322 Oct 2003

Publication series

NameAPBME 2003 - IEEE EMBS Asian-Pacific Conference on Biomedical Engineering 2003

Conference

ConferenceIEEE EMBS Asian-Pacific Conference on Biomedical Engineering 2003 (IEEE EMBS APBME2003)
Abbreviated titleIEEE EMBS APBME2003
PlaceJapan
CityKyoto-Osaka-Nara
Period20/10/0322/10/03

Research Keywords

  • Firing rate
  • IPFM model
  • Low-pass filtering
  • Neural coding

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