A successive laminar flow extraction for plant medicine preparation by microfluidic chip

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Weiwei Qin
  • Yang He
  • Jinyi Xiao
  • Shengwang Liang
  • Shumei Wang
  • Yue Sun

Detail(s)

Original languageEnglish
Article number61
Journal / PublicationMicrofluidics and Nanofluidics
Volume23
Issue number4
Publication statusPublished - 1 Apr 2019
Externally publishedYes

Abstract

Liquid–liquid solvent extraction is frequently used in the purification of active ingredients from plants, and repeated extraction by different solvents with different polarity is often demanded to improve purity. According to this demand, two kinds of laminar flow extraction were designed on the microfluidic chip, i.e. a three-phase laminar chip and a successive laminar flow chip, and compared with a current two-phase chip. P. ginseng was used as a model plant to demonstrate extraction performance, and ether and n-butanol were used as the degrease solvent and extraction solvent, respectively. The results demonstrated that the extraction efficiency of a successive laminar flow chip is higher than that of a three-phase laminar flow chip, and that of both chips are higher than that of a two-phase chip. The chip method provided a new way to extract active ingredients from plants, which should be easily automated and integrated with other units to develop a complex system for sample preparation and ingredient detection.

Research Area(s)

  • Laminar flow, Microfluidics, P. ginseng, Solvent extraction

Bibliographic Note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to lbscholars@cityu.edu.hk.

Citation Format(s)

A successive laminar flow extraction for plant medicine preparation by microfluidic chip. / Qin, Weiwei; He, Yang; Xiao, Jinyi; Liang, Shengwang; Wang, Shumei; Li, Paul C. H.; Sun, Yue.

In: Microfluidics and Nanofluidics, Vol. 23, No. 4, 61, 01.04.2019.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review