A smart DNA-gold nanoparticle probe for detecting single-base changes on the platform of a quartz crystal microbalance

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

19 Scopus Citations
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Author(s)

  • Hui Li
  • Shiyan Xiao
  • Dongbao Yao
  • Michael Hon-Wah Lam
  • Haojun Liang

Detail(s)

Original languageEnglish
Pages (from-to)4670-4673
Journal / PublicationChemical Communications
Volume51
Issue number22
Online published10 Feb 2015
Publication statusPublished - 18 Mar 2015

Abstract

A design of DNA-gold nanoparticle probe-fueled DNA strand displacements for detecting single-base changes on the platform of a quartz crystal microbalance with random sequences was developed. After optimizing and testing the detection system, it has been successfully applied to detect mutation of a realistic sequence associated with human cancer, thereby indicating that this method has potential applicability in general. This journal is

Citation Format(s)

A smart DNA-gold nanoparticle probe for detecting single-base changes on the platform of a quartz crystal microbalance. / Li, Hui; Xiao, Shiyan; Yao, Dongbao et al.

In: Chemical Communications, Vol. 51, No. 22, 18.03.2015, p. 4670-4673.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review