A smart DNA-gold nanoparticle probe for detecting single-base changes on the platform of a quartz crystal microbalance

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

18 Scopus Citations
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Original languageEnglish
Pages (from-to)4670-4673
Journal / PublicationChemical Communications
Volume51
Issue number22
Online published10 Feb 2015
Publication statusPublished - 18 Mar 2015

Abstract

A design of DNA-gold nanoparticle probe-fueled DNA strand displacements for detecting single-base changes on the platform of a quartz crystal microbalance with random sequences was developed. After optimizing and testing the detection system, it has been successfully applied to detect mutation of a realistic sequence associated with human cancer, thereby indicating that this method has potential applicability in general. This journal is