A smart DNA-gold nanoparticle probe for detecting single-base changes on the platform of a quartz crystal microbalance

Hui Li, Shiyan Xiao, Dongbao Yao, Michael Hon-Wah Lam*, Haojun Liang*

*Corresponding author for this work

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    22 Citations (Scopus)

    Abstract

    A design of DNA-gold nanoparticle probe-fueled DNA strand displacements for detecting single-base changes on the platform of a quartz crystal microbalance with random sequences was developed. After optimizing and testing the detection system, it has been successfully applied to detect mutation of a realistic sequence associated with human cancer, thereby indicating that this method has potential applicability in general. This journal is
    Original languageEnglish
    Pages (from-to)4670-4673
    JournalChemical Communications
    Volume51
    Issue number22
    Online published10 Feb 2015
    DOIs
    Publication statusPublished - 18 Mar 2015

    Fingerprint

    Dive into the research topics of 'A smart DNA-gold nanoparticle probe for detecting single-base changes on the platform of a quartz crystal microbalance'. Together they form a unique fingerprint.

    Cite this