A selective fluorescent probe for thiols based on α,β- unsaturated acyl sulfonamide

Huatang Zhang; Ping Wang; Yanxin Yang; Hongyan Sun

doi:10.1039/c2cc35513b

A selective fluorescent probe for thiols based on α,β- unsaturated acyl sulfonamide

Huatang Zhang, Ping Wang, Yanxin Yang, Hongyan Sun

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

62 Citations (Scopus)

Abstract

We report herein a novel fluorescent probe based on α,β- unsaturated acyl sulfonamide to detect thiols. The probe has good water solubility and reacts with thiols under aqueous conditions. It reacts selectively with cysteine but not with the other natural amino acids. The probe was subsequently applied to detect intracellular thiols. © 2012 The Royal Society of Chemistry.

Original language	English
Pages (from-to)	10672-10674
Journal	Chemical Communications
Volume	48
Issue number	86
DOIs	https://doi.org/10.1039/c2cc35513b
Publication status	Published - 7 Nov 2012

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title = "A selective fluorescent probe for thiols based on α,β- unsaturated acyl sulfonamide",

abstract = "We report herein a novel fluorescent probe based on α,β- unsaturated acyl sulfonamide to detect thiols. The probe has good water solubility and reacts with thiols under aqueous conditions. It reacts selectively with cysteine but not with the other natural amino acids. The probe was subsequently applied to detect intracellular thiols. {\textcopyright} 2012 The Royal Society of Chemistry.",

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T1 - A selective fluorescent probe for thiols based on α,β- unsaturated acyl sulfonamide

AU - Zhang, Huatang

AU - Wang, Ping

AU - Yang, Yanxin

AU - Sun, Hongyan

PY - 2012/11/7

Y1 - 2012/11/7

N2 - We report herein a novel fluorescent probe based on α,β- unsaturated acyl sulfonamide to detect thiols. The probe has good water solubility and reacts with thiols under aqueous conditions. It reacts selectively with cysteine but not with the other natural amino acids. The probe was subsequently applied to detect intracellular thiols. © 2012 The Royal Society of Chemistry.

AB - We report herein a novel fluorescent probe based on α,β- unsaturated acyl sulfonamide to detect thiols. The probe has good water solubility and reacts with thiols under aqueous conditions. It reacts selectively with cysteine but not with the other natural amino acids. The probe was subsequently applied to detect intracellular thiols. © 2012 The Royal Society of Chemistry.

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UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-84867321849&origin=recordpage

U2 - 10.1039/c2cc35513b

DO - 10.1039/c2cc35513b

M3 - RGC 21 - Publication in refereed journal

C2 - 23010879

SN - 0009-241X

VL - 48

SP - 10672

EP - 10674

JO - Chemical Communications

JF - Chemical Communications

IS - 86

ER -

A selective fluorescent probe for thiols based on α,β- unsaturated acyl sulfonamide

Abstract

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