A Remotely Controlled Transformable Soft Robot Based on Engineered Cardiac Tissue Construct

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

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Author(s)

  • Xiaomin Han
  • Yuwei Hu
  • Yiming Luo
  • Zi Chen

Detail(s)

Original languageEnglish
Article number1900006
Journal / PublicationSmall
Volume15
Issue number18
Online published25 Mar 2019
Publication statusPublished - 3 May 2019

Abstract

Many living organisms undergo conspicuous or abrupt changes in body structure, which is often accompanied by a behavioral change. Inspired by the natural metamorphosis, robotic systems can be designed as reconfigurable to be multifunctional. Here, a tissue-engineered transformable robot is developed, which can be remotely controlled to assume different mechanical structures for switching locomotive function. The soft robot is actuated by a muscular tail fin that emulates the swimming of whales and works as a cellular engine powered by the synchronized contraction of striated cardiac microtissue constructs. For a transition of locomotive behavior, the robot can be optically triggered to transform from a spread to a retracted form, which effectively changes the bending stiffness of the tail fins, thus minimizing the propulsion output from the “tail fin” and effectively switching off the engine. With the unprecedented controllability and responsiveness, the transformable robot is implemented to work as a cargo carrier for programmed delivery of chemotherapeutic agents to selectively eradicate cancer cells. It is believed that the realization of the transformable concept paves a pathway for potential development of intelligent biohybrid robotic systems.

Research Area(s)

  • biohybrid devices, photoresponsive systems, soft robots, targeted drug delivery, tissue engineering, transformable robots

Citation Format(s)

A Remotely Controlled Transformable Soft Robot Based on Engineered Cardiac Tissue Construct. / Xu, Bingzhe; Han, Xiaomin; Hu, Yuwei; Luo, Yiming; Chen, Chia-Hung; Chen, Zi; Shi, Peng.

In: Small, Vol. 15, No. 18, 1900006, 03.05.2019.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal