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A pH-responsive fluorescence probe and photosensitiser based on a tetraamino silicon(IV) phthalocyanine

Xiong-Jie Jiang, Pui-Chi Lo, Sin-Lui Yeung, Wing-Ping Fong, Dennis K. P. Ng

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

Abstract

A novel tetraamino silicon(iv) phthalocyanine has been prepared, of which the fluorescence emission and reactive oxygen species generation efficiency are greatly enhanced at lower pH in the range of ca. 5-7, making it a promising pH-controlled and tumour-selective fluorescence probe and photosensitiser for photodynamic therapy. © The Royal Society of Chemistry 2010.
Original languageEnglish
Pages (from-to)3188-3190
JournalChemical Communications
Volume46
Issue number18
DOIs
Publication statusPublished - 2010
Externally publishedYes

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