A machine learning model to classify aortic dissection patients in the early diagnosis phase

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalNot applicablepeer-review

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Original languageEnglish
Article number2701
Journal / PublicationScientific Reports
Issue number1
Online published25 Feb 2019
Publication statusPublished - 2019



Aortic dissection is one of the most clinical-challenging and life-threatening cardiovascular diseases associated with high morbidity and mortality. Aortic dissection requires fast diagnosis and timely therapy. Any delay or misdiagnosis can cause severe consequence to aortic dissection patients with even higher mortality. To better help physicians identify the potential dissection within the scope of all misdiagnosed patients, this paper describes a method which is developed with data mining methods for aortic dissection patient classification and prediction in the phase of early diagnosis. Various machine learning algorithms were used to build the models which were all trained and tested on the patient dataset with cross validation. Among them, Bayesian Network model achieved the best performance by predicting at a precision rate of 84.55% with Area Under the Curve (AUC) value of 0.857. On this basis, the Bayesian Network model can help physicians better with early diagnosis of aortic dissection in clinical practice. Beyond this study, more data from diverse regions and the internal pathology can be crucial to further build a universal model with broader predictive power.

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