A luminescence switch-on probe for terminal deoxynucleotidyl transferase (TdT) activity detection by using an iridium(III)-based i-motif probe

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Lihua Lu
  • Modi Wang
  • Li-Juan Liu
  • Chung-Hang Leung
  • Dik-Lung Ma

Detail(s)

Original languageEnglish
Pages (from-to)9953-9956
Journal / PublicationChemical Communications
Volume51
Issue number49
Online published18 May 2015
Publication statusPublished - 21 Jun 2015

Abstract

An iridium(III) complex exhibiting higher responce towards i-motif DNA over dsDNA and ssDNA was employed for the construction of a TdT activity detection platform. The assay exhibited a linear signal enhancement for TdT in the concentration range of 0 to 8 U mL-1, and the limit of detection for TdT was 0.25 U mL-1.

Citation Format(s)

A luminescence switch-on probe for terminal deoxynucleotidyl transferase (TdT) activity detection by using an iridium(III)-based i-motif probe. / Lu, Lihua; Wang, Modi; Liu, Li-Juan et al.

In: Chemical Communications, Vol. 51, No. 49, 21.06.2015, p. 9953-9956.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review