A luminescence switch-on probe for terminal deoxynucleotidyl transferase (TdT) activity detection by using an iridium(III)-based i-motif probe

Lihua Lu; Modi Wang; Li-Juan Liu; Chun-Yuen Wong; Chung-Hang Leung; Dik-Lung Ma

doi:10.1039/c5cc02790j

Author(s)

Lihua Lu
Modi Wang
Li-Juan Liu
Chung-Hang Leung
Dik-Lung Ma

Detail(s)

Original language	English
Pages (from-to)	9953-9956
Journal / Publication	Chemical Communications
Volume	51
Issue number	49
Online published	18 May 2015
Publication status	Published - 21 Jun 2015

Link(s)

DOI	DOI https://doi.org/10.1039/c5cc02790j Final Published version
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Link to Scopus	https://www.scopus.com/record/display.uri?eid=2-s2.0-84931281905&origin=recordpage
Permanent Link	https://scholars.cityu.edu.hk/en/publications/publication(66acbebc-4ae1-4757-9277-adbcaa9bce97).html

Abstract

An iridium(III) complex exhibiting higher responce towards i-motif DNA over dsDNA and ssDNA was employed for the construction of a TdT activity detection platform. The assay exhibited a linear signal enhancement for TdT in the concentration range of 0 to 8 U mL^-1, and the limit of detection for TdT was 0.25 U mL^-1.

Citation Format(s)

[ RIS ] [ BibTeX ]

A luminescence switch-on probe for terminal deoxynucleotidyl transferase (TdT) activity detection by using an iridium(III)-based i-motif probe. / Lu, Lihua; Wang, Modi; Liu, Li-Juan et al.

In: Chemical Communications, Vol. 51, No. 49, 21.06.2015, p. 9953-9956.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review

Lu, L, Wang, M, Liu, L-J, Wong, C-Y, Leung, C-H & Ma, D-L 2015, 'A luminescence switch-on probe for terminal deoxynucleotidyl transferase (TdT) activity detection by using an iridium(III)-based i-motif probe', Chemical Communications, vol. 51, no. 49, pp. 9953-9956. https://doi.org/10.1039/c5cc02790j

Lu, L., Wang, M., Liu, L-J., Wong, C-Y., Leung, C-H., & Ma, D-L. (2015). A luminescence switch-on probe for terminal deoxynucleotidyl transferase (TdT) activity detection by using an iridium(III)-based i-motif probe. Chemical Communications, 51(49), 9953-9956. https://doi.org/10.1039/c5cc02790j

Lu L, Wang M, Liu L-J, Wong C-Y, Leung C-H, Ma D-L. A luminescence switch-on probe for terminal deoxynucleotidyl transferase (TdT) activity detection by using an iridium(III)-based i-motif probe. Chemical Communications. 2015 Jun 21;51(49):9953-9956. Epub 2015 May 18. doi: 10.1039/c5cc02790j

Lu, Lihua ; Wang, Modi ; Liu, Li-Juan et al. / A luminescence switch-on probe for terminal deoxynucleotidyl transferase (TdT) activity detection by using an iridium(III)-based i-motif probe. In: Chemical Communications. 2015 ; Vol. 51, No. 49. pp. 9953-9956.