A general palladium-catalyzed method for alkylation of heteroarenes using secondary and tertiary alkyl halides
Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Author(s)
Detail(s)
| Original language | English |
|---|---|
| Pages (from-to) | 13573-13577 |
| Journal / Publication | Angewandte Chemie - International Edition |
| Volume | 53 |
| Issue number | 49 |
| Publication status | Published - 1 Dec 2014 |
| Externally published | Yes |
Link(s)
Abstract
A general alkylation of heterocycles using a simple palladium catalyst is reported. Most classes of heterocycles, including indoles and pyridines, efficiently coupled with unactivated secondary and tertiary alkyl halides. An alkyl radical addition to neutral heteroarenes is most likely involved.
Research Area(s)
- Alkyl radicals, C-H activation, Heterocycles, Palladium, Single electron transfer
Citation Format(s)
A general palladium-catalyzed method for alkylation of heteroarenes using secondary and tertiary alkyl halides. / Wu, Xiaojin; See, Jessica Wei Ting; Xu, Kai et al.
In: Angewandte Chemie - International Edition, Vol. 53, No. 49, 01.12.2014, p. 13573-13577.
In: Angewandte Chemie - International Edition, Vol. 53, No. 49, 01.12.2014, p. 13573-13577.
Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
